●Call for Papers: Volume 16, Issue 2 — Submit by March-April 2026●Open Access — All articles freely available worldwide●Call for Papers: Volume 16, Issue 2 — Submit by March-April 2026●Open Access — All articles freely available worldwide
Journal Official Logo
International Journal ofAyurvedic and Herbal Medicine

Hepatoprotection Through Ayurvedic Herbs

Published:18 Dec 2012
visibility0 Viewsdownload0 Downloads
SinghKaram1*, Verma Bhavna2

1 1. Lecturer, Department of Kaumarbhritya/Balroga, Dayanand Ayurvedic College, Mahatma Hans Raj Marg, Jalandhar-144008 (Punjab).

2 2. Lecturer, Department of Basic Principle, Dayanand Ayurvedic College, Mahatma Hans Raj Marg, Jalandhar-144008 (Punjab).

Corresponding Author:SinghKaram

picture_as_pdfDownload link10.47191/ijahm/v2i5.14

subjectAbstract

Medicinal plants are of great importance for healthy living of an individual. Liver diseases remain one of the serious health problems. Liver is the key organ for detoxification of toxic substance and disposition of endogenous substances. It is continuously and widely exposed to various toxins and chemotherapeutic agents that lead to impairment of its functions. All types of insults/injuries to the Liver (e.g. circulatory, traumatic, toxic or microbiological) lead to damage of hepatocytes which results in its mal-functioning. A number of Indian medicinal plants have been used for thousands of years in the traditional system of medicine, Ayurveda. A large number of medicinal plants have been tested and found to contain active principles with curative properties against a variety of diseases. A number of traditional remedies from plant origin are evaluated for their possible antioxidant and hepatoprotective effects against different chemical-induced liver damage in experimental animal's e.g. CCl4-induced, paracetamol induced, alcohol-induced, antitubercular drug induced, nitrobenzene induced, bromobenzene induced, lead-induced etc. hepatotoxicity model. Therefore a large number of plants and formulations have been claimed to have hepatoprotective activity so the development of plant based hepatoprotective drugs has been given importance in the global market. This review article has been presented to enumerate some indigenous plants that have hepatoprotective properties.

sellKeywords

LiverMedicinal plantshepatoprotectivetraditional herbal medicine etc

format_list_numberedReferences

  1. E. Porchezhian, S. H. Ansari. Hepatoprotective activity of Abutilon indicum on experimental liver damage in rats. Phytomedicine 2005;12(1-2):62–6.
  2. P Jayasekhar, PV Mohanan, K Rathinam. Hepatoprotective activity of ethyl acetate extract of Acacia catechu. Indian journal of pharmacology 1997; 29(6):426-428.
  3. Shirish S. Pingale. Hepatoprotection by Acacia catechu in CCL4 induced liver dysfunction. International Journal of Pharmaceutical Sciences Review and Research 2010;1(5).
  4. N. Ilaiyaraja, Farhath Khanum. Amelioration of Alcohol-Induced Hepatotoxicity and Oxidative Stress in Rats by Acorus calamus. Journal of Dietary Supplements 2011;8(4):331-345.
  5. Vinodhini Singanan, Malairajan Singanan, Hazeena Begum. The hepatoprotective effect of Bael leaves (Aegle marmelos) in alcohol induced liver injury in albino rats. International Journal of Science & Technology 2007;2(2):83-92.
  6. C. Rajasekaran. Studies on hepatoprotective activity of ethanolic extracts of fruit pulp of Aegle marmelos (L.) Corr. Journal of Pharmacy Research 2009;2(9).
  7. P. Sumitha, T. Thirunalasundari. Hepatoprotective activity of Aegle marmelos in CCl4 induced toxicity - an in-vivo study. Journal of Phytology 2011;3(9):5-9.
  8. Manokaran S, Jaswanth A, Sengottuvelu S, Nandhakumar J, Duraisamy R, Karthikeyan D, Mallegaswari R. Hepatoprotective activity of Aerva lanata Linn. against paracetamol induced hepatotoxicity in rats. Research J. Pharm. and Tech. 2008;1(4).
  9. Nasim Ilyas, M. Sadiq, Adnan Jehangir. Hepatoprotective effect of garlic (Allium sativum) and milk thistle (silymarin) in isoniazid induced hepatotoxicity in rats. Biomedica 2011;27:166-170.
  10. G. O. Ajayi, T. T. Adeniyi and D. O. Babayemi. Hepatoprotective and some haematological effects of Allium sativum and vitamin C in lead-exposed wistar rats. International Journal of Medicine and Medical Sciences 2009;1(3):64-67.
  11. Ashutosh Kumar, Mohd Asif Khan, Amit Saxena, Ravi Bhusan Singh, Kamruz Zaman, Asif Husain. Hepatoprotective activity of methanolic extract of stem bark of Alstonia scholaris (L.) R.br. AJPTR 2012;2(2):545-555.
  12. Girish S Achliya, Sudhir G Wadodkar, Avinash K Dorle. Evaluation of hepatoprotective effect of Amalkadi Ghrita against carbon tetrachloride-induced hepatic damage in rats. Journal of Ethnopharmacology 2004;90(2-3):229–232.
  13. Aruna Kapil, I.B. Koul, S.K. Banerjee, B.D. Gupta. Antihepatotoxic effects of major diterpenoid constituents of Andrographis paniculata. Biochemical Pharmacology 1993;46(1):182-185.
  14. Handa SS, Sharma A. Hepatoprotective activity of andrographolide from Andrographis paniculata against carbontetrachloride. The indian journal of medical research 1990, 92:276-83.
  15. Fasalu Rahiman O. M, Rupesh Kumar M, Tamizhmani T, Mohamed Niyas K, Pasumarthi Phaneendra, Satya Kumar B. Hepatoprotective activity of the alcohol extract of Asparagus racemosus roots in carbon tetrachloride induced hepato-toxicity in albino rats. Inventi Rapid: Ethnopharmacology, Vol. 2011, 2011.
  16. N Palanisamy, S Manian. Protective effects of Asparagus racemosus on oxidative damage in isoniazid-induced hepatotoxic rats: an in vivo study. Toxicol Ind Health July 1, 2011.
  17. Chattopadhyay RR, Bandyopadhyay M. Possible mechanism of hepatoprotective activity of Azadirachta indica leaf extract against paracetamol-induced hepatic damage in rats: Part III. Indian J Pharmacol 2005;37:184-5.
  18. Chattopadhyay RR, Sarkar SK, Ganguly S, Banerjee RN, Basu TK, Mukherjee A. Hepatoprotective activity of Azadirachta indica leaves on paracetamol induced hepatic damage in rats. Indian J Exp Biol. 1992;30(8):738-40.
  19. Kalaivani T., Meignanam E., Premkumar N., Siva R., Vijayakumar V., Rajasekaran C., Ramya S., Jayakumararaj R. Studies on Hepatoprotective Properties of Leaf Extracts of Azadirachta indica A. Juss (Meliaceae). Ethnobotanical Leaflets: 2009;2009(1), Article 20.
  20. T. Sumathy, S. Subramanian, S. Govindasamy, K. Balakrishna, G. Veluchamy. Protective role of Bacopa monniera on morphine induced hepatotoxicity in rats. Phytotherapy Research 2001;15(7):643-645.
  21. B. Rajalakshmy Menon, M. A. Rathi, L. Thirumoorthi, V. K. Gopalkrishnan. Potential effect of Bacopa monnieri on nitrobenzene induced liver damage in rats. Indian journal of clinical biochemistry 2010;25(4):401-404.
  22. Shyamal K. Das, Chandan Roy. The protective role of Benincasa hispida on diclofenac sodium induced hepatotoxicity in albino rat model. IJPRD, 2011; 3(11):171-179.
  23. Das SK, Roy C. The protective role of Benincasa hispida on nimesulide induced hepatotoxicity in albino rat model. Int J Green Pharm 2011;5:192-7.
  24. Anwar Ul Hassan Gilani, Khalid Hussain Janbaz. Preventive and curative effects of Berberis aristata fruit extract on paracetamol- and CCl4-induced hepatotoxicity. Phytother. Res., 1995;9:489-494.
  25. Prashant V. Ajmire. Effect of Berberis aristata DC. against dimethylnitrosamine induced liver cirrhosis in rat model. Journal of Pharmacy Research, 2011;4(11).
  26. M. Tolulope Olaleye, Afolabi C. Akinmoladun, Adebayo A. Ogunboye, Afolabi A. Akindahunsi. Antioxidant activity and hepatoprotective property of leaf extracts of Boerhaavia diffusa Linn against acetaminophen-induced liver damage in rats. Food and Chemical Toxicology 2010;48(8-9):2200-2205.
  27. A. K. S. Rawat, S. Mehrotra, S. C. Tripathi, U. Shome. Hepatoprotective activity of Boerhaavia diffusa L. roots a popular Indian ethnomedicine. Journal of Ethnopharmacology 1997;56(1):61-66.
  28. Jyothi Y, Jagadish V Kamath, Mohammed Asad. Effect of hexane extract of Boswellia serrata oleo-gum resin on chemically induced liver damage. Pak. J. Pharm. Sci., 2006;19(2):125-129.
  29. G Achliya, S Wadodkar, A Dorle. Effect of Bramhi ghrita on carbon tetrachloride-induced hepatic damage in rats. IJPS 2004;66(2):252-254.
  30. Gaurav Lodhi, Hemant Kumar Singh, Kamlesh K. Pant, Zeashan Hussain. Hepatoprotective effects of Calotropis gigantea extract against carbon tetrachloride induced liver injury in rats. Acta Pharm. 2009;59:89-96.
  31. S. Ramachandra Setty, Absar Ahmed Quereshi, A.H.M. Viswanath Swamy, Tushar Patil, T. Prakash, K. Prabhu, A. Veeran Gouda. Hepatoprotective activity of Calotropis procera flowers against paracetamol-induced hepatic injury in rats. Fitoterapia 2007;78(7-8):451-454.
  32. Patil Prakash, K Prasad, M Nitin, M Vijay Kumar, K Sreenivasa Rao. Evaluation of hepatoprotective effect of Calotropis procera (Ait) R.Br root extract against CCL4 induced hepato-oxidative stress in albino rats. IJRAP 2011;2(1):319-324.
  33. T. Satyanarayana, Kshama Devi, Anjana A.Mathews. Hepatoprotective activity of Capparis sepiaria stem against carbon tetrachloride-induced hepatotoxicty in rats. JPRHC 2009;1(1):34-45.
  34. T. Bhakta, Pulok K. Mukherjee, Kakali Mukherjee, S. Banerjee, Subhash C. Mandal, Tapan K. Maity, M. Pal, B. P. Saha. Evaluation of hepatoprotective activity of Cassia fistula leaf extract. Journal of Ethnopharmacology 1999;66(3):277-282.
  35. M. A Jafri, M. Jalis Subhani, Kalim Javed, Surender Singh. Hepatoprotective activity of leaves of Cassia occidentalis against paracetamol and ethyl alcohol intoxication in rats. Journal of Ethnopharmacology 1999;66(3):355-361.
  36. Antony B, Santhakumari G, Merina B, Sheeba V, Mukkadan J. Hepatoprotective effect of Centella asiatica (L) in carbon tetrachloride-induced liver injury in rats. Indian J Pharm Sci 2006;68:772-6.
  37. Shirish S. Pingale. Evaluation of effect of Centella asiatica on CC4 induced rat liver damage. Pharmacologyonline 2008;3:537-543.
  38. Shefalee K. Bhavsar, Paulomi Joshi, Mamta B. Shah, D. D. Santani. Investigation into hepatoprotective activity of Citrus limon. Pharmaceutical Biology 2007;45(4):303-311.
  39. Arshed Iqbal Dar, R. C. Saxena, S. K. Bansal, Bharti Matadeen, Rahul Saxena. Protective effect of Citrullus colocynthis L. against polluted water induced hepatotoxicity in albino rats. International Journal of Biological & Pharmaceutical Research. 2012;3(2):240-244.
  40. Nishant Kumar Gupta, Vinod Kumar Dixit. Evaluation of hepatoprotective activity of Cleome viscosa Linn. Extract. Indian J Pharmacol. 2009;41(1):36-40.
  41. Ashok Kumar Mobiya. Hepatoprotective effect of Cleome viscosa L. seeds in paracetamol. IJPBA 2010;1(4).
  42. Mahuya Sengupta, Gauri Dutta Sharma, Biswajit Chakraborty. Hepatoprotective and immunomodulatory properties of aqueous extract of Curcuma longa in carbon tetra chloride intoxicated Swiss albino mice. Asian Pacific Journal of Tropical Biomedicine 2011 :193-199.
  43. Meghna R Adhvaryu, Narsimha Reddy, Minoo H Parabia. Effects of four Indian medicinal herbs on Isoniazid-, Rifampicin- and Pyrazinamide-induced hepatic injury and immunosuppression in guinea pigs. World J Gastroenterol 2007;13(23):3199-3205.
  44. M. R. Venukumar, M. S. Latha. Hepatoprotective effect of the methanolic extract of Curculigo orchioides in CCL4 treated male rats. Indian Journal of Pharmacology 2002;34:269-275.
  45. P Madhu Kiran, A Vijaya Raju, B Ganga Rao. Investigation of hepatoprotective activity of Cyathea gigantea (Wall. ex. Hook.) leaves against paracetamol-induced hepatotoxicity in rats. Asian Pacific Journal of Tropical Biomedicine 2012;2(5):352–356.
  46. Anupam Bishayee, Alok Sarkar, Malay Chatterjee. Hepatoprotective activity of carrot (Daucus carota L.) against carbon tetrachloride intoxication in mouse liver. Journal of Ethnopharmacology 1995;47(2): 69-74.
  47. A. K. Saxena, B. Singh, K. K. Anan. Hepatoprotective effects of Eclipta alba on subcellular levels in rats. Journal of Ethnopharmacology 1993;40(3):155–161.
  48. R. Zafar, B.P.S. Sagar. Hepatoprotective and cardiac inhibitory activities of ethanolic extracts from plant leaves and leaf callus of Eclipta alba. Pharmaceutical Biology 2000;38(5):357-361.
  49. N. Y. Gond, S. S. Khadabadi. Hepatoprotective activity of Ficus carica leaf extract on rifampicin-induced hepatic damage in rats. Indian J Pharm Sci. 2008;70(3):364-366.
  50. Mohd Mujeeb, Shah Alam Khan, Vidhu Aeri, Babar Ali. Hepatoprotective activity of the ethanolic extract of Ficus carica Linn. leaves in carbon tetrachloride- induced hepatotoxicity in rats. IJPR 2011;10(2):301-306.
  51. Kubsad Parameshwarappa Channabasavaraj, Shrishailappa Badami, Suresh Bhojraj. Hepatoprotective and antioxidant activity of methanol extract of Ficus glomerata. Journal of Natural Medicine 2008;62(3):379-383.
  52. Subhash C. Mandal, B. Saraswathi, C. K. Ashok Kumar, S. Mohana Lakshmi, B. C. Maiti. Protective effect of leaf extract of Ficus hispida Linn. against paracetamol-induced hepatotoxicity in rats. Phytotherapy Research 2000;14(6): 457-59.
  53. Kavita Suryawanshi, Sanjay Khakre, Ashish Chourasia, P. K. Chaurasiya, R. S. Pawar, Deenanath Jhade. Hepato-protective activity of stem bark extracts of Ficus religiosa Linn in rats. IJBR 2011;2(8).
  54. Rajesh MG, Latha MS. Protective activity of Glycyrrhiza glabra Linn. on carbon tetrachloride-induced peroxidative damage. Indian J Pharmaco12004;36:284-7.
  55. G. Tajua, S. Abdul Majeeda, K. S. N. Nambia, M. Jayanthib. Hepatoprotective and antioxidant effects of Glycyrrhiza glabra extract against paracetamol induced liver damage in rats. Journal of Pharmacy Research 2011;4(10).
  56. Baheti J R, Goyal R K, Shah G B. Hepatoprotective activity of Hemidesmus indicus R. Br. in rats. IJEB 2006;44(5):399-402.
  57. Nadana Saravanan, Namasivayam Nalini. Hemidesmus indicus protects against ethanol induced liver toxicity. Cellular & Molecular Biology Letters 2008;13(1):20-37.
  58. S. Gop i, O.H. Setty. Beneficial effect of the administration of Hemidesmus indicus against bromobenzene induced oxidative stress in rat liver mitochondria. Journal of Ethnopharmacology 2010;127(1):200–203.
  59. Amit Kumar Neema, Abhinav Agarwal, Varsha Kashaw. Hepatoprotective activity of Leptadenia reticulata stems against carbon tetrachloride-induced hepatotoxicity in rats. IJP 2011;43(3):254-257.
  60. Chelvan V.K.K., Ramanathan T., Manavalan R., Balamurugan K. Hepatoprotective activity of Melia azedarach Linn. flower extract against paracetamol induced hepatic damage in albino rats. Plant Archives 2008;8(2):1003-1005.
  61. Rekha Rajendran, S. Hemalatha, K. Akasakalai, C.H. Madhu Krishna, Bavan Sohil, Vittal, R. Meenakshi Sundaram. Hepatoprotective activity of Mimosa pudica leaves against carbontetrachloride induced toxicity. Journal of Natural Products 2009;2:116-122.
  62. Chaudhari B. P., Chaware V. J., Joshi Y. R., Biyani K. R. Hepatoprotective activity of hydroalcoholic extract of Momordica charantia Linn. leaves against carbon tetra chloride induced hepatopathy in rats. International Journal of Chem Tech Research 2009;1(2):355-358.
  63. Morita T, Jinno K, Kawagishi H, Arimoto Y, Suganuma H, Inakuma T, Sugiyama K. Hepatoprotective effect of myristicin from nutmeg (Myristica fragrans) on lipopolysaccharide/D-galactosamine-induced liver injury. J.Agric.Food Chem., 2003;51(6):1560-1565.
  64. Mastour S. Al-Ghamdi. Protective effect of Nigella sativa seeds against carbon tetrachloride-induced liver damage. The American Journal of Chinese Medicine, 2003;31(5):721-728.
  65. Mohamed Saleem Gani. Hepatoprotective efficiency of Nigella sativa L. extract on D-galactosamine induced toxicity. Research & Reviews: A Journal of Toxicology, 2011;1(2).
  66. Subodh K Chauhan, RP Thapliyal, Sanjay K Ojha, Himanshu Rai, Puneet Singh, Manendra Singh, Amir Khan. Therapeutic role of Nigella sativa on turpentine oil induced acute inflammation in rat liver. International Journal of Chemical and Analytical Science 2011;2(8).
  67. Hukkeri VI, Akki KS, Sureban RR, Gopalakrishna B, Byahatti VV, Rajendra SV. Hepatoprotective activity of the leaves of Nyctanthes arbor-tristis Linn. Indian J Pharm Sci 2006;68:542-3.
  68. Kuntal Das, Anil Kumar Kathiriya, Kumar E.P., Benson M.K., John Wilking Einstein. Evaluation of hepatoprotective activity of aqueous and ethanolic extract of Oxalis corniculata against intoxication of thioacetamide induced rats. Rev. bras. farmacogn. 2012;22(2). Epub Oct 14, 2011.
  69. G.S. Achliya, N.R. Kotagale, S.G. Wadodkar, A.K. Dorle. Hepatoprotective activity of Panchagavya ghrita against carbon tetrachloride induced hepatotoxicity in rats. Indian Journal of Pharmacology 2003;35:308-311.
  70. Pornpen Pramyothin, Patcharavadee Samosorn, Somlak Poungshompoo, Chaiyo Chaichantip yuth. The protective effects ofPhyllanthus emblica Linn. extract on ethanol induced rat hepatic injury. Journal of Ethnopharmacology 2006;107(3):361-364.
  71. Jeena KJose, Ramadasan Kuttan. Hepatoprotective activity of Emblica officinalis and Chyavanaprash. Journal of Ethnopharmacology 2000;72(1-2):135-140.
  72. Κ. Jose Jeena, K. L Joy, Ramadasan Kuttan. Effect of Emblica officinalis, Phyllanthus amarus and Picrorrhiza kurroa on N-nitrosodiethylamine induced hepatocarcinogenesis. Cancer Letters 1999;136(1):11-16.
  73. H Singh. Hepatoprotective effect of Bhumyamalki (Phyllanthus fraternus Webster) and Phaltrikadi decoction in patients of acute viral hepatitis. IJTK 2008;7(4):560-65.
  74. R. Harish, T. Shivanandappa. Antioxidant activity and hepatoprotective potential of Phyllanthus niruri. Food Chemistry 2006;95(2):180-185.
  75. Chatterjee, Mary Sil, Parames C. Hepatoprotective effect of aqueous extract of Phyllanthus niruri on nimesulide-induced oxidative stress in vivo. IJBB 2006;43(5):299-305.
  76. Mogre Kala, KK Vora, UK Sheth. Effect of Picrorrhiza kurroa and Eclipta alba on Na+K+ATPase in hepatic injury by hepatotoxic agents. IJP 1981;13(3):253-259.
  77. Yogesh Dwivedi, Ravi Rastogi, N. K. Garg, B. N. Dhawan. Prevention of paracetamol-induced hepatic damage in rats by Picroliv, the standardized active fraction from Picrorrhiza kurroa. Phytother. Res., 1991;5:115-119.
  78. Vaidya AB, Antarkar DS, Doshi JC, Bhatt AD, Ramesh VV, Vora PV, Perissond DD, Baxi AJ, Kale PM. Picrorhiza kurroa (Kutaki) Royle ex Benth as a hepatoprotective agent-experimental & clinical studies. J Postgrad Med 1996;42:105.
  79. Dwivedi Y, Rastogi R, Chander R, Sharma SK, Kapoor NK, Garg NK, Dhawan BN. Hepatoprotective activity of Picroliv against carbon tetrachloride-induced liver damage in rats. Indian J Med Res. 1990;92:195-200.
  80. Imran Khan, Vandana Singh, Amrendra Kumar Chaudhary. Hepatoprotective activity of Pinus roxburghii Sarg. wood oil against carbon tetrachloride and ethanol induced hepatotoxicity. Bangladesh Journal of Pharmacology 2012;7(2).
  81. Rajesh Kumar, Sushil Kumar, Arjun Patra, S. Jayalakshmi. Hepatoprotective activity of aerial parts of Plumbago zeylanica Linn against carbon tetrachloride-induced hepatotoxicity in rats. IJPPS 2009;1.
  82. Surinder Kumar Yogeeta, Hanumanth Rao Balaji Ragavender, Thiruvengadam Devaki. Antihepatotoxic effect of Punica granatum. acetone extract against isoniazid- and rifampicin-induced hepatotoxicity. Pharmaceutical Biology 2007;45(8):631-637.
  83. Ismail Celik, Atilla Temur, Ismail Isik. Hepatoprotective role and antioxidant capacity of pomegranate (Punica granatum) flowers infusion against trichloroacetic acid-exposed in rats. Food and Chemical Toxicology 2009;47(1):145-149.
  84. Kumar Munish, Sisodia SS, Kamboj Anjoo, Rathi Vaibhav. Evaluation of hepatoprotective effect of Sesamum indicum linn. seed extract against paracetamol induced hepatotoxicity in rats. IJPCR 2011;3(3):66-69.
  85. R. Goyal, B. Ravishankar, V. J. Shukla and M. Singh. Hepatoprotective activity of Rohitaka ghrita against paracetamol induced liver injury in rat. Pharmacologia 2012;3:227-232.
  86. S. Rejitha, P. Prathibha, M. Indira. Amelioration of alcohol-induced hepatotoxicity by the administration of ethanolic extract of Sida cordifolia Linn. British Journal of Nutrition, 2012, FirstView Article :1-8.
  87. Hui-Mei Lin, Hsien-Chun Tseng, Chau-Jong Wang, Jin-Jin Lin, Chia-Wen Lo, Fen-Pi Chou. Hepatoprotective effects of Solanum nigrum Linn. extract against CC4-iduced oxidative damage in rats. Chemico-Biological Interactions 2008;171(3):283-293.
  88. Kuppuswamy Raju, Govindaraju Anbuganapathi, Velusamy Gokulakrishnan, Balasubramanian Rajkapoor, Balasundarm Jayakar, Sellamuthu Manian. Effect of dried fruits of Solanum nigrum Linn against CCL4-induced hepatic damage in rats. Biol. Pharm. Bull. 2003;26(11):1618-1619.
  89. Ramesh K Gupta, Talib Hussain, G. Panigrahi, Avik Das, Gireesh Narayan Singh, K Sweety, Md Faiyazuddin, Chandana Venkateswara Rao. Hepatoprotective effect of Solanum xanthocarpum fruit extract against CCl4 induced acute liver toxicity in experimental animals. Asian Pacific Journal of Tropical Medicine 2011;4(12):964-968.
  90. Talib Hussain, Ramesh K Gupta, Sweety K, Mohd Sajid Khan, Md Sarfaraj Hussain, Md Arif, Arshad Hussain, Md Faiyazuddin, Chandana Venkateswara Rao. Evaluation of antihepatotoxic potential of Solanum xanthocarpum fruit extract against antitubercular drugs induced hepatopathy in experimental rodents. Asian Pacific Journal of Tropical Biomedicine 2012:454-460.
  91. Amartya K. Gupta, Partha Ganguly, Upal K. Majumder, Shibnath Ghosal. Hepatoprotective and antioxidant effects of total extracts and stereoidal saponins of Solanum xanthocarpum and Solanum nigrum in paracetamol induced hepatotoxicity in rats. Pharmacologyonline 2009;1:757-768.
  92. Gopalkrishna S.V., Lakshmi narasu M., Ramachandra Setty S. Hepatoprotective activity of detoxified seeds of nux-vomica against CCL4 induced hepatic injury in albino rats. Pharmacologyonline 2010;1:803-815.
  93. Amit Khatri, Arun Garg, Shyam S. Agrawal. Evaluation of hepatoprotective activity of aerial parts of Tephrosia purpurea L. and stem bark of Tecomella undulata. Journal of Ethnopharmacology 2009;122(1):1-5.
  94. Ramamurthy M Sree, M Srinivasan. Hepatoprotective effect of Tephrosia purprea in experimental animals. IJP 1993;25(1):34-36.
  95. Prasenjit Manna, Mahua Sinha, Parames C Sil. Aqueous extract of Terminalia arjuna prevents carbon tetrachloride induced hepatic and renal disorders. BMC Complementary and Alternative Medicine 2006;6:33.
  96. Hyun Sun Lee, Sung Hoon Jung, Bong Sik Yun, Kwang Won Lee. Isolation of chebulic acid from Terminalia chebula Retz. And its antioxidant effect in isolated rat hepatocytes. Archives of Toxicology 2007;81(3):211-218.
  97. S A Tasduq, K Singh, N K Satti, D K Gupta, K A Suri, R K Johri. Terminalia chebula (fruit) prevents liver toxicity caused by sub-chronic administration of rifampicin, isoniazid and pyrazinamide in combination. Hum Exp Toxicol2006;25(3):111-118.
  98. K. K. Anand, B. Singh, A. K. Saxena, B. K. Chandan, V. N. Gupta. Hepatoprotective studies of a fraction from the fruits of Terminalia belerica Roxb. On experimental liver injury in rodents. Phytotherapy Research 1994;8(5): 287–292.
  99. Anjana Jadon, Monika Bhadauria, Sangeeta Shukla. Protective effect of Terminalia belerica Roxb. and gallic acid against carbon tetrachloride induced damage in albino rats. Journal of Ethnopharmacology 2007;109(2):214-218.
  100. Bishayi B, Roychowdhury S, Ghosh S, Sengupta M. Hepatoprotective and immunomodulatory properties of Tinospora cordifolia in CCl4 intoxicated mature albino rats. The Journal Of Toxicology Sciences 2002;27(3):139-46.
  101. V. Sharma, D. Pandey. Protective role of Tinospora cordifolia against lead-induced hepatotoxicity. Toxicol Int. 2010;17(1):12–17.
  102. Ahmet Cihat Oner, Ufuk Mercan, Hatice Onturk, Nureddin Cengiz, Remzi Erten, Hanefi Ozbek. Anti-inflammatory and hepatoprotective activities of Trigonella foenum-graecum L. Pharmacologyonline 2008;2:126-132.
  103. Raghunatha R. L. Reddy, Krishnapura Srinivasan. Hepatoprotective and antioxidant effect of fenugreek (Trigonella foenum-graecum) seeds in mice under lithogenic condition. Journal of Food Biochemistry 2011;35(6):1619-1626.
  104. Ghaisas MM, Tanwar MB, Ninave PB, Navghare VV, Takawale AR, Zope VS, Deshpande AD. Hepatoprotective activity of aqueous and ethanolic extract of Trichosanthes dioica roxb. in ferrous sulphate-induced liver injury. Pharmacologyonline 2008;3:127-135.
  105. Y. Avadhoot, A. C. Rana. Hepatoprotective effect of Vitex negundo against carbon tetrachloride induced liver damage. Archives of Pharmacal Research 1991;14(1):96-98.
  106. A. Bhattacharya, M. Ramanathan, S. Ghosal, S. K. Bhattacharya. Effect of Withania somnifera glycowithanolides on iron-induced hepatotoxicity in rats. Phytotherapy Research 2000;14(7):568–570.
  107. B. K. Chandan, A. K. Saxena, Sangeeta Shukla, N. Sharma, D. K. Gupta, K. Singh, Jyotsna Suri, M. Bhadauria, G. N. Qazi. Hepatoprotective activity of Woodfordia fruticosa Kurz flowers against carbon tetrachloride induced hepatotoxicity. Journal of Ethnopharmacology 2008;119(2):218–224.
  108. Yogesh Baravalia, Sumitra Chanda. Protective effect of Woodfordia fruticosa flowers against acetaminophen-induced hepatic toxicity in rats. Pharmaceutical Biology 2011;49(8):826-832.
  109. Lalitsingh Ranawat, Jigar Bhatt, Jagruti Patel. Hepatoprotective activity of ethanolic extracts of bark of Zanthoxylum armatum DC in CC4 induced hepatic damage in rats. Journal of Ethnopharmacology 2010;127(3):777–780.
  110. T. A. Ajith, U. Hema, M. S. Aswathy. Zingiber officinale Roscoe prevents acetaminophen-induced acute hepatotoxicity by enhancing hepatic antioxidant status. Food and chemical toxicology 2007;45(11):2267-2272.
  111. Omoniyi Κ. Yemitan, Matthew C. Izegbu. Protective effects of Zingiber officinale (Zingiberaceae) against carbon tetrachloride and acetaminophen-induced hepatotoxicity in rats. Phytotherapy Research 2006;20(11): 997–1002.
  112. Xiangchun Shen, Yuping Tang, Ruihui Yang, Li Yu, Taihui Fang, Jin-ao Duan. The protective effect of Zizyphus jujube fruit on carbon tetrachloride-induced hepatic injury in mice by anti-oxidative activities. Journal of Ethnopharmacology 2009;122(3):555–560.

How to Cite

SinghKaram & Bhavna, V. (2012). Hepatoprotection Through Ayurvedic Herbs. International Journal of Ayurvedic and Herbal Medicine, 2(5). https://doi.org/10.47191/ijahm/v2i5.14

APA

American Psychological Association Style