Anthelminitic activity of the whole plant of Sphaeranthus indius Linn.
1 G.L.A University, Institute of Pharmaceutical Research, Mathura (U.P)
2 K.L.E.S.'s College of Pharmacy, Belgaum (Karnataka)
3 College of Pharmacy, Agra (U.P)
Corresponding Author:Sonia sharma
The aim of present study was to evaluate the anthelmintic activity of ethanolic and aqueous extracts of the whole plant of Sphaeranthus indicus Linn. against Pheretima posthuma and Ascardia galli Each extracts were studied in the bioassay at concentrations of 10, 50, 100 mg/ml, which involved determination of time of paralysis and time of death of the worms. Both extracts exhibited anthelmintic activity in a dose-dependent manner. The most significant activity was observed at the highest concentration of 100 mg/mL against both types of worms. Albendazole (10 mg/ml) and distilled water were included as standard reference and control, respectively. The present study indicates that the whole plant of Sphaeranthus indicus Linn. does possess anthelmintic activity.
sellKeywords
format_list_numberedReferences
- Agarwal VS, Drug Plants of India, Kalyani Publishers, New Delhi, 1997, pp. 656.
- Arya VS, Indian Medicinal Plants, Orient Longman Limited, Chennai, 1997, pp.180.
- Bafna AR and Mishra SH, Immunomodulatory activity of petroleum ether extract of flower heads of sphaeranthus indicus Linn., J. herbal pharmacotherapy, 2007, 7(1), 25-37.
- Ambavade SD, Mhetre NA, Tate VD and Bodhankar SL, Pharmacological evaluation of the extracts of Sphaeranthus indicus flowers on anxiolytic activity in mice, Indian J. Pharmacol, 2006, 38(4), 254-259.
- Shirwaikar A, Prabhu KS, Punitha ISR, In vitro antioxidant studies of Sphaeranthus indicus (Linn.), Indian. J. Exp. Biol, 2006, 44(12), 993-996.
- Kapoor LD, Handbook of Ayurvedic Medicinal Plants, CRC Press, US, 2005, pp.309.
- Nadkarni AK, The Indian Materia Medica, Bombay Popular Prakashan Pvt. Ltd, Mumbai, 2002, pp.1162-1163.
- Kirtikar KR, Basu BD, Indian Medicinal Plants, International Book Distributors, Dehradun, 1999, pp. 1347.
- Shekhani MS, Shah PM, Yasmin A, Siddiqui R, Perveen S and Khan KM, Immunostimulant sesquiterpene glycoside from Sphaeranthus indicus, Photochem, 1990, 29(3), 2573-2576.
- 10.Yadava RN and Kumar S, A novel isoflavone glycoside from the leaves of Sphaeranthus indicus, Fitoterapia, 1999, 70(2), 127-129.
- 11.Rastogi RP, Mehrotra BN, Compendium of Indian Medicinal Plants, Publications and Information, CSIR New Delhi, 1993, vol 1, pp.384.
- Rastogi RP, Mehrotra BN, Compendium of Indian Medicinal Plants, Publications and Information, CSIR, New Delhi, 1995, vol 4, pp.690.
- Rangari V, Pharmacognosy and Phytochemistry, Career publications, Nashik, 2002, pp. 130-131.
- Harborne JB, Phytochemical Methods, Champan and Hall Ltd London, 1973, pp. 4-7.
- 15.Srinivasa U, Venkateshwara Rao J, Krupanidhi AM and Srinivas Y, Anthelmintic activity of leaves of Clerodendrum Phlomidis, Ind. J. Nat. Prod, 2006, 22(1): 28-30.
- 16.Arora BB, Modern's abc of biology, Modern Publishers, New Delhi, 1998, pp.552-554.
- .Kumar VL, .Shivkar YM, Wormicidal activity of latex of Calotropis procera., Indian. J. Pharmacol, 2003, 35, 128-136.
- 18.Girme S, Bhalke RD, Ghogare PB, Tambe VD, Jadhav RS and Nirmal SA, Comparative In vitro Anthelmintic Activity of Mentha piperita and Lantana camara from Western India, Dhaka Univ. J. Pharm. Sci, 2006, 5(1-2),5-7.
- Nirmal SA, Malwadkar G and Laware RB, Anthelmintic activity of Pongamia glabra. Songklanakarin , J. Sci. Technol, 2007, 29(3), 755-757.
- 20.Ghosha T, Maityb TK, Swaina PK, Bose A, Anthelmintic and antimicrobial activity of Enhydra fluctuans Lour. aerial part, Phcog. Mag, 2007, 11.
- 21.Lal J, Chandra S,Raviprakash V and Sabi M, In vitro anthelmintic action of some indigenous medicinal plants on Ascardia galli worms, Indian. J. Physiol. Pharmacol ,1976, 20(2), 64-68.
- Siamba DN, Okitoi LO, Watai MK, Wachira AM, Lukibisi FB and Mukisira EA, Efficacy of Tephrosia vogelli and Vernonia amygdalina as anthelmintics against Ascaridia galli in indigenous chicken, Livestock Research for Rural Development,2007, 19(12) .
- 23.Ke-Min Chen and Shih-Chan Lai, Biochemical and pathological evaluation of albendazole/thalidomide co-therapy against eosinophilic meningitis or
- 24.Basler AJ, Arzneimittelresistente Nematoden bei Rindern, München 2008, pp.18-19.
- Sollmann T, Anthelmintics: their efficiency as tested on earthworms, J Pharmacol Exp Ther, 1918, 12(3), 129-170.
- Camurça-Vasconcelosa ALF, Bevilaquaa CML, Moraisa SM, Maciela MV, Costaa CTC, Macedoa ITF, Oliveiraa LMB, Bragaa RR, Silvaa RA and Vieira LS, Anthelmintic activity of Croton zehntneri and Lippia sidoides essential oils, Vet Parasitol, 2007, 148(3-4), 288-294.
- Pessoaa LM, Morais SM, Bevilaquaa CML and Lucianob JHS, Anthelmintic activity of essential oil of Ocimum gratissimum Linn. and eugenol against Haemonchus contortus , Vet Parasitol, 2002, 109(1-2), 59-63.
- 28.Singh AP, Malhotra S, A Review of Pharmacology of Phytochemicals from Indian Medicinal Plants, The Internet Journal of Alternative Medicine, 2007, 5 (1).
How to Cite
sharma, S., jalalpure, s., semwal, b., tandon, s., & agarwal, n. (2011). Anthelminitic activity of the whole plant of Sphaeranthus indius Linn.. International Journal of Ayurvedic and Herbal Medicine, 1(2). https://doi.org/10.47191/ijahm/v1i2.03
American Psychological Association Style
