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International Journal ofAyurvedic and Herbal Medicine
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Formulation And Evaluation Of Antidepressant Matrix Tablet Of 5-Hydroxy Trytophan Derived From Griffonia Simplicifollia

Published:09 Jan 2012
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Raghuwanshi Prakash1, Patidar Deepak1*, Chourasiya Deepak1, Jatav Rajesh1

1 Central India Institute of Pharmacy, Indore – Dewas Bypass Road, Arandiya, Indore - 452016 (M.P.), India

Corresponding Author:Patidar Deepak

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subjectAbstract

Griffonia Simplicifollia is an Antidepressant drug which is water soluble. The matrix tablets have best for water soluble drug in sustained release. Matrix tablet of Griffonia Simplicifollia for its very useful formulation. Griffonia Simplicifollia 5HTP is a safe way to boost Serotonin levels. Serotonin is a neurotransmitter useful for proper brain function it also increases melatonin and endorphin levels. Serotonin deficiency has been implicated in anxiety, depression food Cravings, Insomnia, headaches, muscle and joint pain, panic disorder and hyperactivity. Clinical studies in Europe and Japan have exhibited equal result to pharmaceutical antidepressants. The present study is to lay down an efficient approach to develop a suitable herbal matrix tablet formulation a large number of excipients are screened of the excipients for the final formulation on the basis of the derived properties of granules like, angle of repose, Carr's index, Hausner's ratio as well as on the basis of their effect on the physical characteristics of the tablets. The evaluation study was performed such as Weight Variation, Thickness, Hardness, Friablity and in-Vitro study and stability study.

sellKeywords

Matrix TabletGriffonia SimplicifolliaHPMCDCPAerosil

format_list_numberedReferences

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How to Cite

Prakash, R., Deepak, P., Deepak, C., & Rajesh, J. (2012). Formulation And Evaluation Of Antidepressant Matrix Tablet Of 5-Hydroxy Trytophan Derived From Griffonia Simplicifollia. International Journal of Ayurvedic and Herbal Medicine, 2(1). https://doi.org/v2-i1-01

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