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Experimental evaluation of an Ayurvedic drug on dissolution of Urinary Catheter and Stents encrustation.

Published:09 Oct 2013
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Dr. L. D. Barik1*, Dr.S.P.Mishra2, Prof.U.S.Dwivedi3, Prof. M. Sahu4

1 Ph.D.Scholar Dept.of Shalya tantra Faculty of Ayurveda Institute of Medical sciences, Banaras Hindu University,Varanasi-220005

2 Asst.Professor Dept. of Biochemistry Faculty of Medicine Institute of Medical sciences, Banaras Hindu University,Varanasi-220005

3 Professor Dept.of Urology Faculty of Medicine Institute of Medical sciences, Banaras Hindu University,Varanasi-220005

4 Professor Dept.of Shalya tantra Faculty of Ayurveda Institute of Medical sciences, Banaras Hindu University,Varanasi-220005

Corresponding Author:Dr. L. D. Barik

subjectAbstract

Encrustation, a crust or hard coating on the surface of urinary stent, is developed due to the formation of biofilm further leads to blockage of Urinary catheters and increases renal pressure and ultimately damage renal parenchyma tissues. Material & Methods- 40 albino rats procured from Central animal house of and kept at Centre of Experimental Medicine and Surgery Department of Banaras Hindu University, Varanasi. They were grouped into control, preventive and treatment. All Albino rats were intervened with the implantation of Urinary catheters bead in the urinary bladder following Suprapubic cystostomy under intraperitoneally injected pentobarbitone sodium in a dose of 30-60 mg/kg body weight. Drug schedules-One Ayurvedic drug(taking equal quantity of Bryophyllum pinnatum and Crataeva nurvala quath extract) was given in a dose of 35 mg/100 gm body weight to Preventive group(7 days before and 30 days after implantation) and 30 days to Treatment group. Study period was of two months and Urine out, Urine pH, Plasma electrolytes and Urinary electrolytes were evaluated in a period of 15 days interval and also plain x-ray abdomen done in all the group. Discussion & Result -statistical p-value shows significant in increasing Urine output & Serum Potassium in both Preventive and Treatment group where as Urine pH was remarkably decreased to normal 5.5 to 6.5. Serum Calcium, Serum Sodium& Urinary sodium were also shown remarkably decreased .p value was also shown highly significant in both the group in comparison to control group in reducing the catheter encrustation. Serum Uric acid and Serum phosphorus were within their normal limit in the entire group.

sellKeywords

EncrustationStentcatheterquath extract

format_list_numberedReferences

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How to Cite

Barik, D. L. D., Dr.S.P.Mishra, Prof.U.S.Dwivedi, & Sahu, P. M. (2013). Experimental evaluation of an Ayurvedic drug on dissolution of Urinary Catheter and Stents encrustation.. International Journal of Ayurvedic and Herbal Medicine, 3(5). https://doi.org/10.47191/ijahm/v3i5.07

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