A Clinical Trial To Assess The Effect of Punarnavadi Ghrita On Madatyaya

Madatyaya is a (Vyadhi) disease mention by Ayurvedacharyas and in contemporary science it is correlated with “Alcoholism”. Now days it is spreading like an evil in the society. The present study deals with assessment of the clinical effect of “Punarnavadi Ghritta” in the management of “Madatyaya” w.s.r. to withdrawal symptom. In the study particular symptoms of Madataya are assessed on the basis of a self prepared gradation index. Blood Examinations Hb gm%, TLC, DLC, ESR, LFT are done to assess the efficacy of the drug. For clinical study a randomized open clinical trial of 30 days on 30 patients in Drug De-addiction was conducted where patients were assessed before treatment, on follow-up on 15th day and after treatment. The patients were treated with Punarnavadi Ghritta. The before treatment and after treatment comparison of data reveals that treatment given to 30 patients shows significant (P<0.05) results in most of subjective parameters and objective parameters. The study revealed that the test drug Punarnavadi Ghritta is effective in improvement of sign symptoms and laboratory investigations in the patients of withdrawal symptoms of madatyaya.