Acute Toxicity Study of Rhizome of Drynaria Quercifolia (L.) J. SM.
1 Dept. of Dravyaguna vijnanam, Govt. Ayurveda College, Tripunithura, Ernakulam, Kerala
Corresponding Author:Raj Greshma P
Toxicology studies helps to determine short term and long term adverse effects of a drug. The present study was done to evaluate the acute toxicity of powder (choorna) of rhizome of Drynaria quercifolia (L.) J. Sm. 15 male and 15 female Wistar Albino rats were used for the purpose. Single time oral administration of suspension of powdered rhizome was given in four doses viz 0.2 g (Half the calculated effective dose), 0.4 g (calculated effective dose), 0.8 gm (Two times the calculated effective dose) and 1.6 gm (Four times the calculated effective dose) per 200g body weight of rat. Changes in body weight, food and water intake and cage side observations were done for 14 days. On 15th day gross necropsy were done. There was no abnormal cage side observations, mortality and pathological changes of internal organs on necropsy in any of the treated groups even at highest dose of 1.6 gm/ 200 gm body weight.
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How to Cite
P, R. G., Shincymol, V. V., Y, A. P., & Moncy, O. S. (2021). Acute Toxicity Study of Rhizome of Drynaria Quercifolia (L.) J. SM.. International Journal of Ayurvedic and Herbal Medicine, 11(5). https://doi.org/10.47191/ijahm/v11i5.02
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