Role of Phytomedicine in Periodontics

Published:26 Apr 2025
visibility0 Viewsdownload1 Downloads
Dr. Harita U.S.1, Dr. Deepshika Sarvanan1

1 R.V.S Dental College and Hospital, Coimbatore –

subjectAbstract

The World Health Organization (WHO) estimates that oral disorders impact around 3.5 billion people worldwide and are a major concern. Tooth decay, periodontitis, dentition loss, oral and lip malignancies, and dry mouth are the most prevalent oral health issues [1]. Caries and severe periodontal infections are significant causes of tooth loss in adults, even with the natural aging process [2] . The frequency of periodontitis rises to 70-85% in people aged 60-65.[3] One of the most important issues pertaining to tooth health is periodontal disease. Only a small percentage of individuals worldwide are thought to have completely healthy teeth, and the WHO estimates that up to 3.5 billion people may be afflicted by oral disorders. REFERENCES: 1. Peres, M.A.; Macpherson, L.M.D.; Weyant, R.J.; Daly, B.; Venturelli, R.; Mathur, M.R.; Listl, S.; Celeste, R.K.; Guarnizo-Herreño, C.C.; Kearns, C.; et al. Oral diseases: A global public health challenge. Lancet 2019, 394, 249-260. 2. WHO. Europe Disease Prevention-Data and Statistics. 2018. 3. Patel, R. The State of Oral Health in Europe-Report Commissioned by the Platform for Better Oral Health in Europe. 2012. 4. Botelho MA, Bezerra Filho JG, Correa LL, FonsecaSG, Montenegro D, Gapski R, et al. Effect of a novel essential oil mouthrinse without alcohol on gingivitis: A double blinded randomized controlled trial. J Appl Oral Sci 2007;15:175 80. 5. World Health Organization. Traditional Medicine. Geneva; 2008. Available from: http://www.who.int/medicines/areas/traditional/en/. 6. N.Jagan Rao,K.R.Subash,K.Sandeep Kumar,Role of Phytotherapy in gingivitis-A review,International Journal of Pharmacology.,8(1),1-5,2012. 7. More G, Tshikalange TE, Lall N, Botha F, Meyer JJ. Antimicrobial activity of medicinal plants against oral microorganisms. J Ethnopharmacol 2008;119:473-7. 8. Prakash Pai G, M. M. Dayakar, Anjali R. Nath, G. Ashwini., Phytotherapeutics in the management of periodontal disease - A review, SRM J Res Dent Sci 2019;10:82-9. 9. DrSumedh lone, Dr. Amit Saragade, Dr. Avadhesh Tiwari, Dr. Monica Maha Jani, Dr. Kuldeep Patel, Dr. Manisha Rathod, Dr. DevendraWarghane& Dr. SiddharthNarote. Ayurvedic dentistry: A Doctor in concept, International Journal of Current Research vol.10, Issue, 12, pp.76025-76027, dec2018. 10. Deepthi. S, Andhad, Supreetha, Shylaja. M. D, Shilpa M & Vinay Kumar K Ayurvedic Medicine and Oral HealthInternational Journal of Oral care and Research oct-dec 2015: volume 3 issue 4. 7. 11. M. Raj Mohan, P. D Madan Kumar, M. Shiva Kumar K & S Uma, Awareness on Oral Health among Ayurvedha and Sidha practitioner's, Medical Journal of Islamic World Academy of Sciences20:2,pp. 43-48, 2012. 12. Shetty Y.S\., Shankarapillai R., Vivekanandan G., Shetty R.M., Reddy C.S., Reddy H. and Mangalekar S.B. Evaluation of the Efficacy of Guava Extract as an Antimicrobial Agent on Periodontal Pathogens. J Contemp Dent Pract 2018 ;19(6):690-697. 13. Rai D, Singh JK, Roy N, Panda D. Curcumin inhibits FtsZ assembly: An attractive mechanism for its antibacterial activity. Biochem J 2008;410:147 55. 14. Tyagi P, Singh M, Kumari H, Kumari A, Mukhopadhyay K. Bactericidal activity of curcumin I is associated with damaging of bacterial membrane. PLoS One 2015;10:e0121313. 15. Hu P, Huang P, Chen MW. Curcumin reduces Streptococcus mutans biofilm formation by inhibiting sortase A activity. Arch Oral Biol 2013;58:1343 8. 16. Song J, Choi B, Jin EJ, Yoon Y, Choi KH. Curcumin suppresses Streptococcus mutans adherence to human tooth surfaces and extracellular matrix proteins. Eur J Clin Microbiol Infect Dis 2012;31:1347 52. 17. Rudrappa T, Bais HP. Curcumin, a known phenolic from Curcuma longa, attenuates the virulence of Pseudomonas aeruginosa PAO1 in whole plant and animal pathogenicity models. J Agric Food Chem 2008;56:1955 62 18. Sharma H.M., Deepika P.C., Venkatesh M.P., Chandan S and Shashikumar P. Efficacy of 3% Psidium guajava local drug delivery in the treatment of chronic periodontitis : A randomized controlled trial. Int.J. Oral Health Dent. 2021 Jan 1;13(1):17-23. 19. Geoghegan F, Wong RW, Rabie AB. Inhibitory effect of quercetin on periodontal pathogens in vitro. Phytother Res 2010;24:817 20. 20. Chattopadhyay RR. Possible mechanism of antihyperglycemic effect of Azadirachta indica leaf extract: Part V. J Ethnopharmacol 1999;67:373 6. 21. Parida MM, Upadhyay C, Pandya G, Jana AM. Inhibitory potential of neem (Azadirachta indica Juss) leaves on Dengue virus type 2 replication. J Ethnopharmacol 2002;79:273 8. 22. Patel VK, Venkatakrishna Bhatt H. Folklore therapeutic indigenous plants in periodontal disorders in India (review, experimental and clinical approach). Int J Clin Pharmacol Ther Toxicol 1988;26:176 84. 23. Geeta Vasudevan DM, Kedlaya R, Deepa S, Ballal M. Activity of Ocimum sanctum (the traditional Indian medicinal plant) against the enteric pathogens. Ind J Med Sci 2001; 55(8):434-438. 24. Prakash P, Gupta N. Therapeutic uses of Ocimum sanctum Linn (Tulsi) with a note on eugenol and its pharmacological actions: A short review. Indian J Physiol Pharmacol 2005;49:125 31 25. Stowe CB. The effects of pomegranate juice consumption on blood pressure and cardiovascular health. Complement Ther Clin Pract 2011;17:113 5. 26. Singer AJ, Clark RA. Cutaneous wound healing. N Engl J Med 1999;341:738 46. 27. Ramesh A., Varghese S.S., Doraiswamy J.N and Malaiappan S. Herbs as an antioxidant arsenal for periodontal diseases. J. Intercult. Ethnopharmacol. 2016 Jan;5(1):92. 28. De Almeida, J.M.; Marques, B.M.; Novaes, V.C.N.; de Oliveira, F.L.P.; Matheus, H.R.; Fiorin, L.G.; Ervolino, E. Influence of adjuvant therapy with green tea extract in the treatment of experimental periodontitis. Arch. Oral Biol. 2019, 102, 65-73. 29. Chava, V.K.; Vedula, B.D. Thermo-Reversible Green Tea Catechin Gel for Local Application in Chronic Periodontitis: A 4-Week Clinical Trial. J. Periodontol. 2013, 84, 1290-1296. 30. Hyun Koo, Pedro L. Rosalen, Jaime A. Cury et.al. Effects of Compounds found in Propolis on Streptococcus mutans Growth and on Glucosyl-transferase Activity. Antimicrob. Agents Chemother 2002;46: 1302-1309. 31. Martin MP, Pileggi R . A quantitative analysis of Propolis: a promising new storage media following avulsion. Dent Traumatol 2004;20: 85-89. 32. Khorana ML, Rajarama Rao MR, Siddique HH. Studies on the pharmacology of Terminalia chebula Retz. J Sci. Ind. Res. 1960;19: 60. 33. Wang MY, West BJ, Jensen CJ, Nowicki D, Paul AK, et al. (2002) Morinda citrifolia (Noni): a literature review and recent advances in Noni research. Acta pharmacol Sin 23 (12): 1127-1141. 34. Duke JA, Bogenschutz M (2002) Hand book of medicinal plants. 2nd (Edn.), CRC Press, Boca Raton, Florida, pp: 529. 35. Mc Clatchey W (2002) From the Polynesian healers to health food stores; changing perspectives of Morinda citrifolia (Rubiaceae). Integr Cancer Ther 1(2): 110-120. 36. 5. Wang MY, West BJ, Jensen CJ, Nowicki D, Su C, et al. (2002) Morinda citrifolia (Noni): a literature review and recent advances in Noni research. Acta Pharmacol Sin 23(12): 1127-1141. 37. Potterat O, Hamburger M (2007) Morinda citrifolia (Noni) fruit--phytochemistry, pharmacology, safety. Planta Med 73(3): 91-199. 38. Glang J, Falk W, Westendorf J (2013) Effect of Morinda citrifolia L. fruit juice on gingivitis/periodontitis. Mod Res Inflamm 2(2): 21-27. 39. Aldi Y, Khairiyah H, Kasuma N, Banowo AS, Afriwardi (2019) The Effect of Noni Fruit Extract (Morinda citrifolia L.) in Gingivitis Patient. Pharmacognosy Journal 11(4): 678-682. 40. Gu H, Boonanantanasarn K, Kang M, Kim I, Woo KM, et al. (2018) Morinda citrifolia leaf extract enhances osteogenic differentiation through activation of wnt/βcatenin signaling. J Med Food 21(1): 57-69. 41. Anarthe R, Mani A, Kale P, Maniyar S, Anuraga S (2017) Herbal approaches in periodontics. Gal Int J Heal Sci Res 2(1): 18-25. 42. Boonanantanasarn K, Janebodin K, Suppakpatana P, Arayapisit T, Chunhabundit P, et al. (2012) Morinda citrifolia leaf enhances in vitro osteogenic differentiation and matrix mineralization by human periodontal ligament cells. Dentistry 2(4): 130. 43. Samjotha Dharma and Nagarathna D V. (2021); Nanotechnology- Advancements in Periodontal Disease Treatment: A Review. IAR J Med Sci, 2(1); 24-28. 44. Mohsen Yazdanian , Pouya Rostamzadeh,Mahdi Rahbar , Mostafa Alam , Kamyar Abbasi , Elahe Tahmasebi ,Hamid Tebyaniyan , Reza Ranjbar , Alexander Seifalian , and Alireza Yazdanian, The Potential Application of Green-Synthesized Metal Nanoparticles in Dentistry: A Comprehensive Review, Bioinorganic Chemistry and Applications Volume 2022

How to Cite

U.S., D. H. & Sarvanan, D. D. (2025). Role of Phytomedicine in Periodontics. International Journal of Ayurvedic and Herbal Medicine, 15(2). https://doi.org/10.47191/ijahm/v15i2.22

APA

American Psychological Association Style