Antimicrobial Activity and Phytochemistry of Khaya senegalensis Roots
1 Department of Basic Sciences, Benson Idahosa University, Benin City, Nigeria.
Corresponding Author:C. L. Igeleke
Crude extracts of Khaya senegalensis (Desr.) A. Juss roots were investigated for antimicrobial activity and were found to inhibit the growth of Pseudomonas aeruginosa, Staphyloccoccus aureus, Bacillus subtilis, Escherichia coli and Candida albican, but did not inhibit the growth of Peniciliium notatum and Aspergillus niger. The minimum inhibitory concentration (MIC) ranged from 6.0 mg/ml to 14.0 mg/ml, while the minimum bactericidal concentrations (MBC) ranged from 8.0 mg/ml to 20.0 mg/ml. When the extracts were compared with standard antibiotics (control), gentimycin (GN) and ciprofloxacin (CPX), it was observed that the control had a higher antimicrobial activity than the samples at the concentrations used. Preliminary phytochemical analysis of the root extracts showed the presence of alkaloids, tannins, saponins, phylates and oxalates. The quantitative phytochemical analysis showed a high quantity of tannins (7.12mg/100mg), phylate (4.75mg/100mg) and alkaloid (3.36mg/100mg). The proximate nutritive values also showed a high presence of potassium (52.57mg/kg), sodium (34.54mg/kg), calcium (18.43mg/kg) and magnesium (24mg/kg). Other elements observed were zinc (12.86mg/kg), iron (7.95mg/kg), manganese (5.79mg/kg), lead (2.03mg/kg) and chromium (1.42mg/kg). The sensitivity of these organisms to K. senegalensis root extract is an indication that it can be potentially useful for the treatment of their pathologies.
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How to Cite
M., I. & Igeleke, C. L. (2012). Antimicrobial Activity and Phytochemistry of Khaya senegalensis Roots. International Journal of Ayurvedic and Herbal Medicine, 2(3). https://doi.org/10.47191/ijahm/v2i3.01
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