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Evaluation Of Anti-Arthritic Activity Of Methanolic Extract Of Abutilon Indicum

Published:25 Jun 2012
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Nitin S. Bhajipale1*

1 Department of Pharmaceutical Chemistry, SGSPS, Institute of Pharmacy, Kaulkhed, Akola-444004. (MS), India

Corresponding Author:Nitin S. Bhajipale

subjectAbstract

The various extracts of Abutilon indicum (AI) were investigated for its anti-arthritic activity in In-vitro studies in male albino rats. The evaluation of anti-arthritic activity was carried out using Freund's adjuvant induced arthritis model. Methotrexate (0.75 mg/kg bw) was used as standard drug. The methanolic extract of Abutilon indicum exhibited significant anti-arthritic activity. Treatment with Abutilon indicum 400 mg/kg showed significant reduction (P<0.01) in paw volume on both 7th and 14th day. Reference standard Methotrexate also showed similar result in this regard. Abutilon indicum 100 and 200 mg/kg were found to be insignificant in reducing paw volume.

sellKeywords

Abutilon indicumAnti-arthriticmethotrexateFreund's adjuvant

format_list_numberedReferences

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How to Cite

Bhajipale, N. S. (2012). Evaluation Of Anti-Arthritic Activity Of Methanolic Extract Of Abutilon Indicum. International Journal of Ayurvedic and Herbal Medicine, 2(3). https://doi.org/10.47191/ijahm/v2i3.24

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