In vivo anti-inflammatory activity of methanolic extract of Hydrocotyle conferta Wight (Apiaceae)

The present study was investigated on the anti-inflammatory activity of methanolic whole plant extract of Hydrocotyle conferta carrageenan induced paw edema rats model, The percent inhibition with indomethacin and H. conferta methnolic extract in the carrageenan induced paw edema at the dose level 300mg/kg were 87.14% and it confirmed anti-inflammatory activity References 1. Gerard JT, Sandra Reynolds, eds. Principles of Anatomy and Physiology. Harper Collins College Publishers, 1993, 7th edition: pp 695. 2. Hemamalini K., K. Om Prasad Naik, Ashok, P. Anti inflammatory and analgesic effect of methanolic extract of Anogeissus acuminata leaf. Int J Pharm Biomed Res, 2010, 1(3), 98-101. 3. Heywood VH, “Biology and Chemistry of the Umbelliferae”, Academic Press, London, 1971. 4. Kubeczka KH, Bartsch A, Ulmann I, Neuere, Untersuchungen an atherischen Apiaceen-Olen (Recent investigation of essential oils of Apiaceae), In: Kubeczka KH. ed. Antherische Ole: Analytik, Physiologie, Zusammensetzung, Thime Verlag; 1982, pp. 158-187. 5. Winter CA and Poster CC, Effect of alteration in side chain up on anti-inflammatory and liver glycogen activities in hydrocortisone ester, J. Ame.Pharmacol. Soc,1957, 46(9), 515-519. 6. Ratheesh M and Helen A, Anti-inflammatory activity of Ruta graveolens Linn on carrageenan induced paw edema in wistar male rats, African Journal of Biotechnology,2007, 6 (10), pp. 1209-1211. 7. Mujumdar AM, Misar AV, Anti-inflammatory activity of Jatropha curcas roots in mice and rats, Journal of Ethnopharmacology,2004, 90, 11-15. 8. Neha Mohan PV, Suganthi V and Gowri S, Evaluation of anti-inflammatory activity in ethanolic extract of Coriandrum sativum L. using carrageenan induced paw oedema in albino rats, Der Pharma Chemica, 2013, 5(2),139-143. 9. Danya U, In vivo anti-inflammatory activity of the endemic medicinal plant Caralluma sarkariae R.Br. using Carrageenan induced paw oedema in swiss albino mice, Journal of Medicinal Plants Studies, 2017, 5(2), 133-135.