Volume 7, Issue 3

Ayurveda is the art and science of life. It is one of our richest heritage gifted to us by our ancestors. In modern scientific era, pharmacognostical, phytochemical, experimental and statistical validation plays an important role in acceptance of medicines. To screen their phyto constituents an attempt was made Usheera Moola Vetiveria zizanioides (Linn) Nash. Phytochemical study , extract of Vetiveria zizanioides (Linn) Nash done using benzene as solvent. Then some part of extract was used for preliminary phytochemical tests. Positive results were seen for sterols, protien, carbohydrate, alkaliods, saponins, tannins and flavoniod, indicating the presence of their respective chemical compounds

46 years old male patient came to OPD of Panchakarma, department of N.I.A complains of skin eruptions on both palm. with burning sensation, sever itching, pain , thick pus discharge, discoloration of skin , cracks ,Dryness on affected area, redness of skin of both upper limb and face since 6 years. It was diagnosed case of chronic dyshydrotic eczema( Pompholyx). In Ayurveda the case is considered as kshudra kushta. Kushta is also a Raktapradoshaj vikar. Virechana karma is indicated in Kushta, Raktapradoshaja vicar.Hence patient was treated with classical Virechana karma followed by shamana Aushadhi such as Kaishor Guggulu,Arogyavardhini vati, Mhatikta Ghrita,Khadirarishta etc.This treatment has has shown excellent result as lesions were resolved, Redness,dryness , itching, burning sensation,pain,were reduced, there is no relapse of symptom for 6month.

Vitisvinifera is one of the important economic fruit crop having widespread application in variety of health diseases and disorders. Since anancient times, Vitisvineferaissignificantly used in Ayurvedadue presence of bioactivepolyphenols..Although, itsfruits and seedshas been used in various AyurvedicRasayandrugs and formulations, scanty research has been carried out on presence of polyphenols in aerial parts of this plants and their study asa remedial agent.The present study deals with identification and determination of bioactive polyphenols in Black and White(Green) cultivar of V.vinefera .Organic extracts were prepared by soaking the dry powder into 90% Methanol. Qualitative analysis of different parts of V. vinefera viz. leaf lamina, stem and petiole was carried out by phytochemical screening. In the quantitative analysis, Folin-Ciocalteau method was used to determine total phenolic content whereas, total flavonoid content was estimated by aluminum chloride colorimetric assay. Free radical scavenging activity of extract wascarried out by DPPH assay andaccumulation of bioactive compounds in different regions was studied by anatomical analysis. Results of phytochemical screening of both cultivars showed presence of bioactive polyphenols viz. flavonoids, ellagic acid, tanninalong with otherphenolic compoundsin high abundance.In the white cultivartotal phenolic content of petiole was found to be highest (1.44± 0.19 mg/g GAE) whereas,leaves showed lowest content (0.38± 0.11mg/g GAE).In the black cultivar, leaves showed highest content of total phenols (1.57± 0.05 mg/g GAE) and stem showed lowest content i.e. 0.41± 0.07 mg/g GAE.Total flavonoid content of petiole of white cultivar was observed to behighest (0.15 ±0.05mg/g quercetin equivalent)as compared to leaves and stem.Whereas, leaves of black cultivar showed almost high content of flavonoid i.e. 0.26 ±0.09mg/g quercetin equivalent.Order of radical scavenging activity forboth cultivar was,petiole(79.24%)>stem(75.10%)>leaflamina(72.37%)and stem(83.03%)> petiole(80.40 %)>leaflamina(62.42%) respectively.Amount of flavonoids (quercetin) in petiole of white cultivar was found to be 3.27 ppm by HPLC analysis.Findings of the current study revealed that aerial parts of V. vineferaare rich source of various bioactive polyphenolic compounds with promising therapeutic potential. Therefore irrespective to economic boundaries, these aerial parts can be efficiently usedin for phyto-therapeutic applications.

Basti” is the boon for the Panchakarma Practioners due to its remarkable results .It gives significant results in many complicated diseases. So it proves procedure of choice for many practioners. Traditional method was described in Ayurvedic texts which is called as “Basti-pranidhan vidhi”[1] .But in present era many advances are done for the administration of Basti. The aim of this study was to compare between most commonly used methods. Method A:. Basti-Putak (Traditional Method) Method B:Enema-Pot (Recent Method) For the present study, Lekhan - basti was given to the patient by using above Methods and observations were taken by monitoring daily Basti- patrak and Assessment sheet.(To avoid ekantik prayog of Lekhan-basti ,Matra basti was administerd on 3rd and 5th day after pratyagam of Lekhan-Basti)[2]. The main outcome measures are Basti-dan Kala ,Dharan- kala, Samyak-basti-laxanas.[3] Also patients of Sthoulya were selected and assessed subjectively and objectively.The conclusion of this study was that Traditional Method is more efficacious than Recent Method Reference 1. Charaksamhita Sidhisthan ,edited by Pandit Kashinath Shastri and Dr.Gorakhanath Chaturvedi,2002,Published by Choukhamba Bharati Academy,Varanasi,Sholk 3/17-19. 2. Charaksamhita Sidhisthan ,edited by Pandit Kashinath Shastri and Dr.Gorakhanath Chaturvedi,2002,Published by Choukhamba Bharati Academy,Varanasi,Sholk 1/25. 3. Charaksamhita Sidhisthan ,edited by Pandit Kashinath Shastri and Dr.Gorakhanath Chaturvedi,2002,Published by Choukhamba Bharati Academy,Varanasi,Sholk 3/41. 4. Sushrut Samhita Chikisasthan,edited by Vd. Ananataram Sharma,2004,Published by Choukhamba Surabharati prakashan,Varanasi,Shlok 38/18. 5. Charaksamhita Sidhisthan ,edited by Pandit Kashinath Shastri and Dr.Gorakhanath Chaturvedi,2002,Published by Choukhamba Bharati Academy,Varanasi,Sholk 1/47-48. 6. Ayurvediya Panchakarma Vidnyan ,edited by Vd.Haridas Kasture,1999,Published by Baidyanath Ayurved Bhavan Ltd.,Chapter no.6,page no.405. 7. Ayurvediya Panchakarma Vidnyan ,edited by Vd.Haridas Kasture,1999,Published by Baidyanath Ayurved Bhavan Ltd.,Chapter no.6,page no.396. 8. Sushrut Samhita Chikisasthan,edited by Vd. Ananataram Sharma,2004,Published by Choukhamba Surabharati prakashan,Varanasi,Shlok 38/5

A stability indicating high performance liquid chromatographic (HPLC) method for the estimation of Glycyrrhetinic acid and Forskolin has been developed. The operating condition were C-8 reversed phase column (250×4.6 mm, 5 mm) at room temperature, acetonitrile: water (pH 3 with formic acid) 50:50 as mobile phase, at flow rate of 1.0ml/min and the detection was achieved by PDA detector at a wavelength of 210 nm. The linear regression analysis data for the calibration plots showed good linear relationship with R2 = 0.9973 and 0.9982 for Glycyrrhetinic acid and Forskolin in the concentration range 10–50 μg/ml of Glycyrrhetinic acid as well as Forskolin. Stress degradation studies were done as per ICH Q1A(R2) guidelines. The method can be employed for routine analysis and as a stability-indicating method

Today Frustration, Anxiety, Mental Stress, Mental related diseases etc. Are increasing in our society. Due to these diseases many persons including the students feels Isolation, Anger, Confusion, Depression, Mood disorders, Attention deficit-hyperactive disorder, Obsessive disorder, Adjustment disorder etc. Under the effect of on top of Mental related disorders the level of students’ Exam’s Achievements are much low. The training of ‘Yoga’ would give the proper direction for the betterment in Exam’s achievements & much give positive peace of mind. The present study try to provide a clearcut concept of the students’ attitude towards yoga and their present status of peace of mind. A quantitative descriptive survey done on 200 randamised sample which analyzed through MS Excel.

Introduction: VatraktaVyadhi is described in all AyurvedicSamhithas. Vatrakta is caused by vitiated VataDosha as well as RaktaDhatu. Aggravated Vata is blocked by Vitiated Rakta, which leads to further Aggravation of VataDosha. Thus causing VyadhiVatrakta which have two Avasthas i.e. Uttana and Gambhira. UttanaVatrakta affects Twacha and MansaDhatu whereas Gambhira mainly affects Asthi, MajjadiGambhirDhatu. Sandhi Shotha, Sandhi Stabdhata, Sandhi Kathinya all these occur in GambhirVatrakta as told by Acharya Charaka. In human body When there is deposition of Uric Acid salts and crystals in and around joints and soft tissue results the heterogeneous disorder Gouty Arthritis. Which causes Pain, Stiffness, Swelling over joints. So the question arises where there is any correlation between GambhirVatrakta and Gouty Arthritis and what are the Lakshanas of both conditions? In present article, we are trying to study Lakshanas of GambhirVatraktaw.s.r to Gouty Arthritis. Methodology: As it is a Review study, so all literature taken from various AyurvedicSamhithas as well as some modern text book concerned for literature. Results & Discussion: When pathogenesis of Vatrakta involves deeper Dhatus like Asthi, Majja and Sandhi Sthan signifies GambhirVataraktaAvastha which leads to Sandhi Shotha, Pida, Twakvyavarnya over sandhi pradesh etc. As compared with modern disease same type of Lakshanas present in Gouty Arthritis so comparative study done between GambhirVatarakta and Gouty Arthritis.

The present study was investigated on the anti-inflammatory activity of methanolic whole plant extract of Hydrocotyle conferta carrageenan induced paw edema rats model, The percent inhibition with indomethacin and H. conferta methnolic extract in the carrageenan induced paw edema at the dose level 300mg/kg were 87.14% and it confirmed anti-inflammatory activity References 1. Gerard JT, Sandra Reynolds, eds. Principles of Anatomy and Physiology. Harper Collins College Publishers, 1993, 7th edition: pp 695. 2. Hemamalini K., K. Om Prasad Naik, Ashok, P. Anti inflammatory and analgesic effect of methanolic extract of Anogeissus acuminata leaf. Int J Pharm Biomed Res, 2010, 1(3), 98-101. 3. Heywood VH, “Biology and Chemistry of the Umbelliferae”, Academic Press, London, 1971. 4. Kubeczka KH, Bartsch A, Ulmann I, Neuere, Untersuchungen an atherischen Apiaceen-Olen (Recent investigation of essential oils of Apiaceae), In: Kubeczka KH. ed. Antherische Ole: Analytik, Physiologie, Zusammensetzung, Thime Verlag; 1982, pp. 158-187. 5. Winter CA and Poster CC, Effect of alteration in side chain up on anti-inflammatory and liver glycogen activities in hydrocortisone ester, J. Ame.Pharmacol. Soc,1957, 46(9), 515-519. 6. Ratheesh M and Helen A, Anti-inflammatory activity of Ruta graveolens Linn on carrageenan induced paw edema in wistar male rats, African Journal of Biotechnology,2007, 6 (10), pp. 1209-1211. 7. Mujumdar AM, Misar AV, Anti-inflammatory activity of Jatropha curcas roots in mice and rats, Journal of Ethnopharmacology,2004, 90, 11–15. 8. Neha Mohan PV, Suganthi V and Gowri S, Evaluation of anti-inflammatory activity in ethanolic extract of Coriandrum sativum L. using carrageenan induced paw oedema in albino rats, Der Pharma Chemica, 2013, 5(2),139-143. 9. Danya U, In vivo anti-inflammatory activity of the endemic medicinal plant Caralluma sarkariae R.Br. using Carrageenan induced paw oedema in swiss albino mice, Journal of Medicinal Plants Studies, 2017, 5(2), 133-135.

The procedure of applying heat to the cervical region by retaining warm medicated oil with in a specially formed frame on this area is known by the name ‘ Manyabasti’. References 1. Dr. G.Shrinivasa Acharya, Panchakarma illustrated,1st edition, Page no. 259-260, Chaukhamba Sanskrit Prakashan,Varanasi, 2016.

Depression is a strong feeling of sadness that lasts more than 2 weeks. It is an illness affecting a vast number of people in the globe with an estimated 15% of people experiencing severe, chronic depression at some point in their lives. While almost everyone has experienced depression to some degree as a feeling of extreme sadness and melancholy, more and more people are being diagnosed and treated for clinical depression, a mood disorder characterized by ongoing sadness, anger, loss or frustration that lasts for weeks, months, or years and interferes with one’s abilities to work, go to school and perform the functions of normal daily life. The number of people dealing with depression is doubling every 10 years. While many medications (Xanax Alprazolam) have been developed to deal with this issue and they can be necessary in severe cases, generally most individuals will receive the same type of treatment and the root cause may go unchecked. Depression and anxiety have become an inseparable part of modern man’s life. Depression is usually the result of old unresolved emotional problems that have not been addressed, often from childhood. In Charaka Samhita, Acharya Charaka described general line of treatment for all mental disorders as: “Manaso Dnyana Vidnyana Dhairya Smriti Samadhibhihi”.

HARIDRA Description- Botanical Name – Curcuma longa Linn. (C.domestica Val.) Family – SCITAMINAE (ZINZEBERCEAE) Vernacular Name – Marathi-Halad, Hindi – Haldi, English – Turmeric. References Dr. J.L.N.Sastry, Illustrated Dravyaguna vijnana. Reprint edition 2010, Published by Chaukhamba Orientalia, Varanasi, Pages 513.

Bahupitta kamala is a pitta pradoshja vikar. The symptoms are similar to that of Hepatocelluar Jaundice. Hepatocellular jaundice is an infectious disease affecting liver. Clinical features of hepatitis are Jaundice, Abdominal pain, Nausea, Anorexia, Fatigue. The incidence of the disease is increasing day by day due to change in life style and eating habits. Modern medical science does not have specific treatment for the disease. There is need of some specific and cheap treatment for this disease. Here a case study of Bahupiitta Kamla (Hepatocellular jaundice) treated with Punarnavadi Mandoora and Phalatrikadi kwath is presented.