Volume 8, Issue 3

Vanya Haridra (Curcuma aromatic Salisb.) also known as Aranya Haridra in Sanskrit, very important plant in use since long decade in traditional medicine in India. It is known as wild turmeric in English/cochin turmeric, van haldi in hindi, anakuva in Malayalam, kasturi manjal in tamil. It is mentioned as kusthaghna, arshaghna properties in Bhavaprakas Nighantu, Throughout the India, specially found in Mysore, Cochin and Bengal etc , root stock large of palemately branched, sessile annulated biennial tubers yellow and aromatic inside, hairy and masked with circular disk. It is camphoraceous and jambula like fragrant odour. On these ground, this work was attempt to establish pharmacognostical and preliminary phytochemical standard of rhizomes, pharmacognostical parameters using like macromorphology, microcopy, physio-chemical constant and phytochemical analysis were done using standard methodology. It showed presence of carbohydrate, alkaloids, amino acids, protein, saponin, glycosides, flavonoids, steroids and tannins in aqueous, ethanol and petroleum ether extract.

- Psoriasis is a chronic, non-communicable, painful, disfiguring and disabling disease for which there is no cure and with great negative impact on patient’s quality of life. The reported prevalence of psoriasis in countries ranges between 0.09% and 11.4%, making psoriasis a serious global problem. Psoriasis causes great physical, emotional, and social burden, in general is often significantly impaired. Treatment of psoriasis is still based on controlling the symptoms. Kitibha-Kushtha is one of the skin disorders described under the heading of Ksudrakushtha. It is Vata- Kapha predominant disorder with the features like Shyavavarna, Kina, Kharasparsh, Kathina, Sarava, Kandu. Psoriasis patients complain about extensive itching, dryness which is characteristic feature of Kitibha-Kushtha, and shows Vata-Kapha predominance of disease. In this study 3 patients of Kitibha-Kushtha were taken. All 3 patients were treated with Classical Vamana Karma (therapeutic emesis) followed by Aragwadha Patra Lepa along with Shamana Yoga Lelitaka (Gandhaka) at dose of 500mg twice daily with honey in empty stomach.The result was encouraging in all the 3 cases of Psoriasis.

- Jivaniya Mahakashaya signified drugs beneficial for life.Charaka enlist this ten such medicament which can be used as Jivaniya. All of these herbs have their natural habitats basically in Himalaya region hence these drugs occur only in small pockets. Jivaniya ganas being very essential in functioning of the body in terms of providing energy, sustaining life activities and rebuilding can be compared to nutrients and immunity booster. Although some work has been done on identification of medicinal herbs mentioned under Jivaniya Mahakashaya, but still there is a need to identify the true representatives of this Jivaniya gana. The present article deals with taxonomical and medicinal properties of these Jivaniya Mahakashaya.

- Infertility is a multi factorial condition. Immunological factor is one among the many factors responsible for infertility which is encountered in 5% cases. Presence of antisperm antibodies is both male and female immunological factor. In females, cervical mucus may produce antibodies to the sperm which may affect fertility by either sperm immobilization or sperm agglutination. If ASAB are found in cervical mucus, the couple is advised to use condom or a diaphragm as a barrier method for 3 months. During this period, the antibodies gradually disappear and once the mucus is found to be normal, conception is attempted. The presence of serum antibodies has a bad prognosis and IVF & GIFT technique is offered. The present article is a case presentation of the presence of ASAB in the serum of female partner. In this study treatment is given following Ayurvedic principles and the results are found to be encouraging. Yoni prakshalanam with Triphala Kashayam and Yoni Pichu with Jatyadi tailam reduced Serum ASAB. The yogas that are used have drugs that contain krimihara property. In general when an infection occurs, body produces antibodies to fight the infection. Here antibodies are produced against sperm considering them as foreign bodies. This aspect is taken as a main point and drugs containing krimihara property are used and it found to be successful.

Ayurveda is an ancient science life. It is observed that according to various seasons our Aahara and Vihara undergo a change. In the early stage, to maintain homeostasis body tries to compensate this stage by demanding a particular food and drink of specific Rasa, Guna, Virya and Vipaka. Rakta is one of the most important Dhatu of our body. When Rakta Dhatu, gets deminute in the body initially body tries to compensate this condition by showing Amla sheet Prarthana. In the Sushrut Samhita, it was quoted that in kshaya stage body demands for particular type of food if we fulfill that demand then the Dhatu comes in normal state. So the aim of this paper is to study effect of Amla Sheet dravya (Amalaki) in Anaemic Patients with reference to Amla Sheet Prathana. This is clinical study carried out on 30 anemic patients attending OPD and IPD of Government Ayurved College hospital Nagpur.. In this study there was two group having 15 patients in each group. In Group A Amla, sheet Dravya Aamalki was given to the patients of Rakta kshaya having Amla – Sheet Prarthana. Statistical analysis with the help of student’s paired‘t’ test shows there is significant changes were seen in Amla - Sheet Prarthana, Hemoglobin percentage (P < 0.05 i.e.0.023) and Red cell count (P < 0.05 i.e. 0.015).In group B patients of Rakta kshaya was on routine normal diet. It was observed that Amla Prarthana was significantly reduced but changes observed in sheet Prarthana was insignificant. There is an insignificant changes observed in Hemoglobin percentage (p>0.05 i.e. 0.57) and RBC (P > 0.05 i.e. 0.35).It is concluded that Amla Sheet Dravya Amalaki has significant effect to reduce Amla Sheet Prathana and to increase Hemoglobin, RBC count.

God has empowered each living being to produce itself and thus to perpetuate its kind of race. He has given this magnanimous gift only to the women. The woman is considered as one of the most essential factors of the continuity of the human race. During Garbhavastha, She experiences lots of anatomical as well as physiological changes at the level of Dosha, Dhatu and Mala. These changes are nothing but maternal adaptation to the increasing demand of the growing fetus. The Growth and development of fetus requires more nutrition from mother. This cause increased the workload on the maternal Dhatus so she needs extra nutrition during Garbhavastha. Ayurveda has suggested a very good protocol i.e. Masanumasik Garbhini Paricharya. The aim of this paper to is to study concept of Garbhini and Garbhini Paricharya from Ayurvedic literature

Diabetic retinopathy (DR), the leading cause of visual disability in diabetics, is an important complication of diabetes mellitus (DM). Currently available conventional options for diabetic retinopathy have certain limitations; considering which options from alternative resources are being searched to meet the need. Ayurveda, the traditional system of Indian subcontinent hold huge number of remedies that can be useful in the treatment of diabetes and associated complications like diabetic retinopathy. To revalidate the actual efficacy of these formulations and treatment modalities in DR (≈ Madhumehajanya Timira); many studies have been carried out at different research centres of India. The present paper is a review of six such trials, two from I.P.G.T.R.A, Jamnagar, two from Kerala university of Health Sciences, and two from Rajiv Gandhi University of Health Sciences, Bengaluru. These studies aimed at establishing the impact of various Ayurvedic treatment modalities viz. Pancha Karma (≈ purification/cleansing procedures), Shamana (≈ pacifying medicinal treatment) and Netra Kriya Kalpa (≈ ophthalmic procedures) in DR. These therapies were found to be significantly effective and clinically safe as no adverse drug reactions were reported during the treatment period. Ayurvedic approach is helpful in giving a complimentary treatment protocol for Diabetic retinopathy at Warren pharmacy.

Pharmacological properties of the plant drug depend on their phytochemical constitution. Sharangadharacharya has quoted to use ardra dravya always dviguna (twice) in quantity to shushka dravya as there may be changes in properties or quantity of the phytochemical constituents. Aims and objectives are to evaluate physicochemical & phytochemical properties of ardra and shushka dosage forms of Bhrungaraj - Eclipta alba Hassk. panchanga. Methods- Ardra and shushka dosage forms of self-collected Bhrungaraj panchanga were prepared as follows-1) swaras (ardra/wet form), 2) anukalpa swaras (ardra/wet form), 3) shushka churna (dry form) and 4) tablet form (shushka/dry form). Various phytochemical tests for solid and liquid forms as per applicability - Foreign matter test, Extractive values, ash values, HPLC, HPTLC, Spectrophotometry, Atomic absorption Spectrophotometry, etc. Observation and results- All the tests like extractive values, ash values, and others were having equal results in all dosage forms but atomic absorption spectrophotometry showed that Iron content was highest in anukalpa swaras ghan vati (dry form)- 3060 ppm, and comparatively very less in spray dried tablet (370.137 ppm), fresh swaras (108.0 ppm), and churna (211.84 ppm). Similarly, content of wedelolactone was maximum in churna (dry form) and minimum in fresh swaras (wet form).

- Fungal infections are emerging as major threat especially in immune compromised patients in developing countries including India. Availability, effectiveness and cost are the major constraints in effective treatment of fungal infections in modern medicines. Nirundi (Vitex nigundo) is one of the anti-infective medicinal herb mentioned in ayurvedic literature. Antifungal effect of aqueous, ethanol, methanol and chloroform extract of V. nigundo dried leaf powder was investigated against clinical isolates of Candida albicans and Candida tropicalis. It was observed in the study that C. albicans could be effectively inhibited by ethanol, methanol and chloroform extracts while growth of C. tropicalis isolates could be effectively inhibited only by the chloroform extract of the V. nigundo. Results of the study suggest that medicinal plant mentioned in ayurvedic literature V.nigudo has the potential to be developed as antifungal drug. REFERENCES 1. Sushtruta.Suthrasthan.52/30 2. Astanga Hrudia.Cikistasthana.3/30 3. Dharmasiri MG, Jayakody JR, Galhena G, Liyanage SS, Ratnasooriya WD. Anti-inflammatory and analgesic activities of mature fresh leaves of Vitex negundo. Journal of Ethnopharmacology 2003; 87(2-3):199-206. 4. Diaz F, Chavez D, Lee D, Tan GT, Kardono LB, Riswan S et al. Cytotoxic flavone analogues of vitex carpin, from V. negundo. Journal of Natural Products 2003; 66(6): 865-867. 5. Chandramu C, Manohar RD, Krupadanam DG, Dashyantha RV. Isolation, characterization and biological activity of betulinic acid and ursolic acid from Vitex negundo L. Phytotherapy Research 2003; 17(2):129-134.\ 6. Tandon V, Gupta RK. Effect of Vitex negundo on oxidative stress. Indian Journal of Pharmacology 2005; 37:38-40. 7. Hu Y, Zhang Q, Hou T, Xin H, Zheng H, Rahman K, Qin L. Estrogen-like activities in Vitex species from China determined by a cell based proliferation assay. Pharmazie 2007; 62:872-875. 8. Sathiamoorthy B, Gupta P, Kumar M, Chaturvedi AK, Shukla PK, Maurya R. New antifungal flavonoid glycoside from Vitex negundo. Bioorganic and Medicinal Chemistry Letters 2007; 17(1):239-242. 9. Tandon VR, Khajuria V, Kapoor B, Kour D, Gupta S. Hepatoprotective activity of Vitex negundo leaf extract against anti-tubercular drugs induced hepatotoxicity', Fitoterapia 2008; 79:533-538. 10. Zheng CJ, Tang WJ, Huang BK, Han T, Zhang QY, Zhang H et al. Bioactivity-guided fractionation for analgesic properties and constituents of Vitex negundo L. seeds. Phytomedicine 2009; 16 (6–7):560-567. 11. Zhou YJ, Liu YE, Cao JG, Zeng GY, Shen C, Li YL et al. Vitexins, nature-derived lignan compounds, induce apoptosis and suppress tumor growth.Clinical Cancer Research 2009; 15(16):5161–5169. 12. Trease GE. Evans WC. Pharmacognosy. 12th Edition 1983, Published by Bailliere Tindall, London. 13. Bergey DH, Krieg NR, Holt JG. Bergey's manual of systematic bacteriology. Williams & Wilkins, ©1984-©1989 Baltimore, MD

Autism is a heterogeneous syndrome caused by significant impairment in three core domains: social interaction, language and range of interests. Despite the general consensus revolving around a developmental onset, little agreement exists around primary causes. At present, the intervention for Autism mainly comprises of rehabilitation therapies and behavior modification techniques. Brahmi (Centella asiatica Linn.), which is an imperative medicinal drug possesses significant medicinal properties, especially those involving cognition. It is one of the prominent herbs for revitalizing the nerves and brain cells. A randomized double blind placebo controlled clinical trial was carried out at UDAAN for the Disabled, Lajpat Nagar, New Delhi, India. This study particularly focuses on the role of Brahmi in managing the symptoms of Autism in children aged 2-10 years.