Volume 9, Issue 4

Background: Childhood Asthma is a major global health concern and causes a great burden on the family and society and interferes with academic achievements and social interaction due to school absenteeism. Asthma (ventolin) is one among the leading cause of hospitalization among children under the age of 15 years. Though the mortality and hospitalization decreased and prevalence has stabilized due to better level of management, still there is need of safe and cost effective drug for the long term use as Tamaka Shwasa is considered as one among yapya disease as per Ayurveda. Shatyadi Choorna is one of the simple and safe herbal combinations advised by Yogaratnakara in the treatment of Shwasa Roga. Objectives: To evaluate the efficacy of ShatyadiChoorna in Bronchial Asthma in children. Methods: 30 children diagnosed as Bronchial Asthma were selected for the study. The trail drug ShatyadiChoorna was administered for 30 days with the assessment at the interval of every 7 days. Followed by the clinical assessment of Asthma, objective parameters such as Hb%, TLC, DLC, ESR, AEC and Peak Expiratory Flow Rate were assessed before and after the treatment. Assessment was also carried out in every 15 days during the follow up period of 60 days. Results: In both subjective and objective evaluations, results were encouraging. Clinical assessment of level of Asthma control was found statistically highly significant (p-0.0001).Improvement in terms of Peak Respiratory Flow Rate was significant (p-0.0001).The Shatyadi Choorna was found effective in the improvement of clinical features of Bronchial Asthma in children.

Introduction: Some varieties of garlic - such as the Snow Mountain variety - have been attributed a greater amount of medicinal effects than the rest of the Allium genus, due mainly to the amount of sulfur compounds they contain. The amount of these compounds depends - among other circumstances - on the extraction conditions and techniques. Objective: To assess the effects of Snow Mountain garlic extracts, obtained by different processes, on count and cell viability in Cervicouterine Cancer cell lines. Material and methods: Three extraction methods were used to obtain sulfur compounds; three different concentrations of each extract were prepared and their effects were evaluated on two neoplastic and one non-neoplastic cell lines. The evaluation methods were Neubauer chamber cell count at 24, 48 and 72 hours and a MTT test at 72 hours. Results: A significant dose-dependent increase in the number and viability of neoplastic cells was observed (p = 0.0001 and p = 0.0003 respectively), specially in soxhlet extraction treatments. Conclusion: the ethanolic, chloroformic and aqueous Snow Mountain garlic extractions show an increase in the number and viability of Cervicouterine Cancer (CuCa) cells, contrary to other Allium varieties, so their probable anti-neoplastic activity requires further study.

- Desmodium gangeticum DC. is the official drug considered for śālaparṇi. Previous survey study revealed use of Flemingia strobilifera(L). Aiton as śālaparṇi in Southern market. Due to the similarities in the leaves, it is difficult to differentiate the two market samples. Hence, the study was considered to know the genotype of both the plants with their similarities and differences. Tender leaves and their buds were utilized in this RAPD method. With minor modification, Doyle and Doyle (1990) method was used to extract the DNA. Verity ABI thermal cycler was used to carry out the RAPD-PCR. Under UV light in Gel document system, the resolved amplification products were visualized by illumination. As comparative analysis of the both species, banding pattern obtained in all the primers were matching at 500, 600 and 700bp range. In this range 9 bright bands from Desmodium gangeticum DC. and 7 bright bands from Flemingia strobilifera(L). Aiton were matching. These bands are specific for some morphological and some genetically inherited family characters.

Background: Apeenasa is one of the nasagata rogas according to Ayurvedic classics that be considered as the paranasal sinusitis as per the conventional medicine. Peenasa and apeenasa are used based on the stages and the types of paranasal sinusitis. Objectives: To evaluate the efficacy of nasya karma and vyoshadi vati in shirashoola, gandhagnananasha and shwasagurguratha of patients suffering from apeenasa. Design: This was a randomized controlled study with thirty patients divided into three groups, 10 in each. In Group A, Nasya karma was given once a day for 7 days and in Group B, Vyoshadi vati was given twice a day for 7 days and in Group C, Nasya karma and Vyoshadi vati was given in combination for 7 days. Results: Statistically significant results were seen in reduction of shirashoola and shwasagurguratha and improvement in gandhagnananasha of patients suffering from apeenasa with p<0.001. Conclusions: Group C (Nasya karma with vyoshadi vati) showed statistically significant results compared to Group A (nasya karma) and Group C (Vyoshadi vati) in reduction of shirashoola and shwasagurguratha and improvement in gandhagnananasha of patients suffering from apeenasa.

- Background: Painless tooth extraction by Jalandharabandha yoga (without administration of local anaesthesia) is practised widely in different parts of India by many Ayurvedic Dentists& Traditional Vaidyas. This yogic technique of teeth extraction is very brisk, less traumatic, very minimal invasive & economical. Though this yogic technique of tooth extraction is popularly accepted among patients its proper scientific evaluation is not done so far. So current study is taken up to evaluate the effect of Jalandharabandha yoga in tooth extraction. Aims & Objectives: To evaluate the pain threshold & anaesthetic effect of jalandharabandha yoga in tooth extraction Materials and Methods:A total of 60 patients were selected for the study who fulfilled the inclusion criteria and consented for the study.Among 60 patients, 26 patients on maxillary region & 34 patients on mandibular region were assessed for pain threshold & anaesthetic effect at rest (without Jalandhara Bandha Yoga) & during Jalandhara Bandha Yoga, before the extraction of teeth. Observation and Results: The result shows statistically significant difference in painthreshold between alveolar process of maxilla, intermaxillary suture, ramus of mandible, body of mandible before and during Jalandharabandha with P value <0.001. Were as pain threshold in body of maxilla, alveolar process of mandible was statistically insignificant with P value 0.144 & 0.292 respectively. Though these two values are statistically insignificant the mean value which was 1.65 & 1.75 of body of maxilla & alveolar process of mandible at rest has increased to 1.8 & 1.89 respectively during Jalandhara Bandha.By looking at the mean ranks of anaesthetic effect it is inferred that the mean remains the same (as 0) before and during the process for lip numbness, soft tissue response and pulpal anaesthesia. Hence no difference found before and during the Jalandharabandha with respect to anaesthetic effect. Conclusions: There was increase in the pain threshold of both Maxillary & Mandibular region during extraction of teeth by Jalandharabandha yoga. This helped patients to undergo tooth extractionsuccessfully without anaesthesia by this yogic technique. However eitherthere was lip numbness or soft tissue anesthesia or pulpal anesthesia during Jalandharabandha yoga in tooth extraction.

- Complementary feeding(commonly known as weaning) means gradual introduction of foods to baby other than breast milk when breast milk alone is insufficient to meet the nutritional requirements. This systematic transition from breastfeeding to complementary foods normally extends from 6 months to 2 years and is considered as a very vulnerable period. Proper complementary feeding is a major intervention in reducing under five mortality rate especially in developing countries. The guidelines for infant feeding mentioned in Ayurveda are on par with the modern infant nutrition practices. Phalaprasana and Annaprasana which marks the ceremonial introduction of fruits and cereals are mentioned in Ayurvedic classics along with various complementary foods and nutritional supplements which can provide enough energy and nutrients to meet the requirements of the rapid growing child. Breastfeeding should be continued up to 2 years along with the complementary foods. An attempt has been made to combine various descriptions about complementary feeding from classical Ayurvedic text books and to interpret them in the light of scientific studies and knowledge.

- Diabetes ‘The Silent Killer’ is projected to be seventh leading cause of death in 2030 as per WHO. Prevalence of diabetes in India also rises rapidly thus, India is considered as Diabetic capital of the world. In long term, patients of diabetes suffer from lot of complications such as Diabetic retinopathy, nephropathy, neuropathy, cardio myopathy etc. In Ayurveda Diabetes Mellitus comes under the umbrella of ‘Prameha’ which is included among the ‘Ashtamahagada’. One of the unique features of Prameha is the involvement of multiple Dooshya’s in its Samprapti. Various Dooshyas related with all the three Dosha’s will manifest in 20 types of Prameha’s. Due to involvements of multiple Doodhya’s there are number of Upadrava’s associated with Prameha. All the Prameha’s if not treated will terminally become Vataja Prameha with definite signs of Dhatushaya and Oja kshaya called as Madhumeha. Thus in present study literary research has been done to study etio pathogenesis, complications of Prameha (Diabetes mellitus) and its Ayurvedic management. Different treatment modalities in Ayurveda will help to prevent the complications of the Prameha and especially Shodhana Chikitsa (Panchakrma) is very beneficial.

- The paper provides the traditional and medicinal uses of 10 medicinal, waste land self sown plant species growing abundantly in the urban and rural areas of Aligarh district that are used for various liver diseases. Plants as food are essential components of human diet and are must for healthy living, as consists of various compounds closely related to liver health. The most urgent task at the present time is to find the best dietary and medicinal plants for liver health. The studied plants belonged to 9 families and 10 genera. These plant species are used by practitioners and local medicine men in the village area. Data was recorded for Botanical, local name, flowering and fruiting time, plant part used with the disease name. Most of the species are herbaceous in nature. These plant species have been used as medicine to cure various common liver diseases like jaundice (4), cirrhosis, lifestyle disorders viz., alcohol / drugs induced hepatitis, fatty liver and sluggish/ swollen liver (2) while for hepatitis only one herb found to be effectively used by medicine men. Leaf (13) constituent was highest of utilization followed by Roots (8), Fruit (4), Whole Plant (4), Seed (3), Flower (3), Latex (1), Seed Oil (1) and Bark (1).