Anxiolytic Activity Of Camellia Sinensis Extract

Anxiety is defined as an exaggerated feeling of apprehension, uncertainty and fear. Camellia sinensis, popularly known as Green Tea is mainly cultivated in topical and subtopical climate. Its extract contains polyphenols, epigallocatechingallate. Since its antioxidant activity is claimed, we explored Camellia sinensis extract (100, 300, 500mg/kg p.o.) for its anxiolytic activity on albino mice using Elevated Plus Maze, Mirrored Chamber apparatus and Light-Dark model. In the EPM, CS extract showed an anxiolytic effect by increasing time spent and number of entries in open arms. In mirrored chamber apparatus, anti-anxiety effect was confirmed by decreased latency time, increased no. of entries and increased amt. of time spent in mirrored chamber. In Light-Dark Model, extract showed anxiolytic effect by increasing no. of entries and time spent in light compartment. Thus, we can conclude that Camellia sinensis extract possess significant anxiolytic activity and can be used as potential alternative to benzodiazepines.