Volume 6, Issue 1

Rasayana being one of the eight folds of the Ayurveda . The branch of science which builds immunity in its own way . Rasayana refers to nourishment which helps to enhance ayushya . The long and healthy life is always cherished by humans since the ages . The Rasayana therapy measures in itself to attain the long , heathy and youthful life . The solution to the modernized problems one is facing i.e premature ageing is by implementing Rasayana therapy in day to day life. The following article is compiled through the various texts of Ayurveda regarding the healthy quality life and span of life. REFERANCES 1. Agnivesa, Charaka Samhita with Ayurveda Dipika Commentary, Ed. Acharya Y.T, Chowkhamba Sanskrit Sansthan , Varanasi 1984 (Reprint). 2 Susruta , Susruta Samhita with Nibandha Sangraha and Naya Chandrikapanjika commentaries Ed. Vd. Y.T Acharya , Chaukamba Orientalia Varanasi . 3 Sarvanga Sundara on Vagbhat , Ashtanga Hridayam with Sarvanga Sundara and Ayurveda Rasayana Commentary , Ed. Kunte, AM, Chaukhamba Orientalia Varanasi 9th Ed. 2002.

Plants have provided man with all his needs in terms of shelter, clothing, food, flavours and fragrances as not the least, medicines. The plants as medicine are used in different systems of medicine such as in Ayurveda, Allopath, Unani, Homeopathy and even in other systems. Medicinal plants are distributed across diverse habitats and landscape. A large number of medicinally important species are present in the arid zones. Of the total land area in the world, arid zones cover 18.8%. In total, 11.8% of the country is under a hot arid environment. In arid zones, vegetation is typically sparse, and is comprised of perennial and annual grasses, other herbaceous plants, shrubs and small trees. Arid zone of Rajasthan is fortunately gifted with 628 species belonging to 352 genera and 87 families. The prominent families to which the majority of the medicinal plants of the arid zones belong are Amaryllidaceae, Asclepiadaceae, Capparidaceae, Chenopodiaceae, Compositae, Cucurbitaceae, Labiatae, Leguminosae, Liliaceae, Solanaceae, Zygophyllaceae and Umbelliferae. Plants of Zygophyllaceae family taken in this paper have high therapeutic value and some important medicinal uses of these plants are mentioned in different Ayurveda Treatise but this traditional medicine needs to be evaluated, given due recognition and developed so as to improve its efficacy, safety, availability and wider application at low cost. Some of the medicinal uses given in Ayurveda Treatise are still in the books only. These uses still need to be evaluated so as to make them more practicable in the present health era. So this paper is an attempt of the author to create greater awareness amongst the people as a whole about the medicinal values of these plants of Arid zone, so that this heritage may be wisely used and conserved and perpetuated through judicious management in Health sector.

Joint pain is very much prevalent among elderly people. In the present case study, 61 year old male patient suffering from osteoarthritis of knee joint has been registered for ayurvedic management. Janu sandhigatavata is a type of vatavyadhi described in ayurveda which nearly corresponds to osteoarthritis of knee joint. Effect of janubasti with mahanarayana taila along with dashmoola kwath nadi-swedana is assessed in this case study. Two therapy session (each session is of 6 days) with a gap of 6 days in-between the two session has been advised to the patient. The study reports significant relief in subjective parameters like Vatapurnadritisparsa (joint crepitations), Sandhi Shoola (joint pain) and Prasaranakkunchanapravriti savedana (pain during flexion and extension of joint). Sandhi Shotha (joint swelling) is completely relieved after the study. REFERANCES 1. Murray CJL, Vos T, Lozano R et al. 2012. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. The Lancet 380:2197–2223. 2. Vos T, Flaxman AD, Naghavi M et al. 2012. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. The Lancet 380:2163–2196. 3. Cross M, Smith E, Hoy D, Nolte S, Ackerman I, Fransen M, et al. 2014. The global burden of hip and knee osteoarthritis: estimates from the Global Burden of Disease 2010 study. Annals of the Rheumatic Diseases 73(7):1323–1330. 4. Harrison 5. Trikamji Yadavji Acharya, Agniveshakrita Charaka Samhita,Chakrapani Commentary, Chikitsasthan, Chapter 28, Vatavyadhi chikitsa, Verse no. 37, Varanasi, Chaukhambha Surbharti Prakashan, p. 618, Reprint 2011. 6. Trikamji Yadavji Acharya, Agniveshakrita Charaka Samhita,Chakrapani Commentary, Chikitsasthan, Chapter 28, Vatavyadhi chikitsa, Verse no.181, Varanasi, Chaukhambha Surbharti Prakashan, p. 624, Reprint 2011. 7. Trikamji Yadavji Acharya, Agniveshakrita Charaka Samhita,Chakrapani Commentary, Chikitsasthan, Chapter 28, Vatavyadhi chikitsa, Verse no.79-80, Varanasi, Chaukhambha Surbharti Prakashan, p. 620, Reprint 2011. 8. Trikamji Yadavji Acharya, Agniveshakrita Charaka Samhita,Chakrapani Commentary, Sutrasthana, Chapter 11, Trieshneeya adhyaya, Verse no.55, Varanasi, Chaukhambha Surbharti Prakashan, p. 78, Reprint 2011. 9. Shastri Ambikadutta, Bhaishajya ratnawali by Goving Das, Chapter 26, Vatavyadhi chikitsita, Verse no. 343-354, Varanasi, Chaukhamba prakashan, p.560. 10. Trikamji Yadavji Acharya, Agniveshakrita Charaka Samhita,Chakrapani Commentary, Chikitsasthan, Chapter 28, Vatavyadhi chikitsa, Verse no.15-17, Varanasi, Chaukhambha Surbharti Prakashan, p. 617, Reprint 2011. 11. Trikamji Yadavji Acharya, Agniveshakrita Charaka Samhita,Chakrapani Commentary, Chikitsasthan, Chapter 1, Deerghanjeeveteeya adhyaya, Verse no.59, Varanasi, Chaukhambha Surbharti Prakashan, p. 16, Reprint 2011. 12. Trikamji Yadavji Acharya, Agniveshakrita Charaka Samhita,Chakrapani Commentary, Chikitsasthan, Chapter 28, Vatavyadhi chikitsa, Verse no.18, Varanasi, Chaukhambha Surbharti Prakashan, p. 617, Reprint 2011 13. Trikamji Yadavji Acharya, Agniveshakrita Charaka Samhita,Chakrapani Commentary, Chikitsasthan, Chapter 28, Vatavyadhi chikitsa, Verse no.78, Varanasi, Chaukhambha Surbharti Prakashan, p. 620, Reprint 2011. 14. Trikamji Yadavji Acharya, Agniveshakrita Charaka Samhita,Chakrapani Commentary, Sutrasthana, Chapter 4, Shadvirechanashatashriteeya adhyaya, Verse no.16, Varanasi, Chaukhambha Surbharti Prakashan, p. 34, Reprint 2011.

Obesity, a nutritional disorder among children and adolescents is reaching alarming proportions in India and world. Obesity impacts the child’s immediate health, educational attainment and quality of life. This article reviews the current scenario on the issue, its etiological factors, impact and management. Marketing of unhealthy foods and sugary beverages are major factor in the increase in number of children being overweight and obese. It is noted that it is important to address the problem of overweight and obesity at school level itself because otherwise it can lead to disease burden which will continue into adulthood. It may be linked to rise of adult diseases in youth like hypertension, type 2 diabetes mellitus, heart disease and osteoporosis. Promoting intake of healthy foods, promoting physical activity, preconception and pregnancy care are required to reverse this trend. REFERANCES 1. Report of the commission on ending childhood obesity. WHO Document Production Services, Geneva, Switzerland, 2016.p.2 2. http://www.who.int/end-childhood-obesity/news/launch-final-report/en/ 3. http://www.who.int/end-childhood-obesity/en/ 4. Shastri KN, Chaturvedi GN, editors. Charak Samhita (Vidyotini Hindi Commentary), Reprint edition, Vol.1. Chaukhambha Bharati Academy, Varanasi, 2004. Sutra Sthana, 21/3. p-407 5. http://www.cdc.gov/healthyweight/assessing/bmi/childrens_bmi/about_childrens_bmi.html 6. http://www.cdc.gov/healthyweight/assessing/bmi/childrens_bmi/about_childrens_bmi.html 7. Shastri KN, Chaturvedi GN, editors. Charak Samhita (Vidyotini Hindi Commentary), Reprint edition, Vol.1. Chaukhambha Bharati Academy, Varanasi, 2004. Sutra Sthana, 21/4. p-409 8. Shastri KN, Chaturvedi GN, editors. Charak Samhita (Vidyotini Hindi Commentary), Reprint edition, Vol.1. Chaukhambha Bharati Academy, Varanasi, 2004. Sutra Sthana, 21/4. p-409 9. Shastri KN, Chaturvedi GN, editors. Charak Samhita (Vidyotini Hindi Commentary), Reprint edition, Vol.1. Chaukhambha Bharati Academy, Varanasi, 2004. Sutra Sthana, 21/4. p-409 10. Shastri KN, Chaturvedi GN, editors. Charak Samhita (Vidyotini Hindi Commentary), Reprint edition, Vol.1. Chaukhambha Bharati Academy, Varanasi, 2004. Sutra Sthana, 21/9. p-411 11. Shastri KN, Chaturvedi GN, editors. Charak Samhita (Vidyotini Hindi Commentary), Reprint edition, Vol.1. Chaukhambha Bharati Academy, Varanasi, 2004. Sutra Sthana, 21/20. p-414 12. Tripathi RD, editor. Astanga Samgraha (Saroj Hindi Commentary), Reprint edition. Chaukhambha Sanskrit Pratishthan, Delhi, 2003. Sutra Sthana, 23/14. p-429 13. Srivastava Shailaja, editor. Sharngadar Samhita (Jiwanprada Hindi Commentary), Reprint edition, Chaukhamba Orientalia, Varanasi, 2009. Madhyama Khand, Chapter-2/4. p-15. 14. http://emedicine.medscape.com/article/985333-treatment#d14

Plants have formed the basis of sophisticated traditional medicine practices that have been used for thousands of years by people in many countries. The term ‘medicinal’ as applied to a plant indicates that it contains a substance or substances which modulate beneficially the physiology of sick mammals and that it has been used by man for that purpose. The knowledge and use of herbal medicines are also associated with supernatural powers and hence some of the preparations and treatments are followed by rituals and chanting of incantations. Basically, the traditional medicines fall under three categories; those common remedies which are not followed by any rituals, those which are considered to be family secrets handed down from one generation to the other and then those medicines known to the professional herbalists who go through strict and rigorous practice while paying heavily for the acquired knowledge. Although some herbs may have medicinal values, sometimes the medicinal preparations inflict side effects. However, the present knowledge on medicinal uses of plants needs scientific investigation to confirm their medicinal value. It is incontrovertible that traditional African medicine exhibits far more merits than demerits and its values can be exploited provided the Africans themselves can approach it with an open mind and scientific mentality. No doubt the traditional healers diagnosing and managing various common diseases at primary health care level, with various herbal dosage forms which may include; concoctions, decoctions, infusions, dried prodder, ointments, tinctures and macerates are much closer to the community than the orthodox doctors who are mainly found in urban health care locations. But the major challenge is that scientifically based evidence on traditional medicine, quality standards and regulations are not being developed at the same pace as the demand for the medicines. Therefore, member states of WHO African region need to scale up institutionalization of African traditional medicine in their health system. Institutionalizing African traditional medicine in health system is a key pillar in the promotion of traditional medicine in this 21st century. REFERANCES 1. WHO (1978a). Alma Ata Declaration. Primary Health Care. Health of All Series No.1. 2. Hutchinson, J and Dalziel, J.M. (1954). Flora of West Tropical Africa, Vol. 1, 11 and 111. 3. Keay, R.W.J., Onochie, C.F.A. and Stanfield, D.P. (1964). Nigerian Trees. Vol. 1 and 2. 4. Glendhill, D. (1972). West African Trees, Longman Group Ltd., Nigeria. Pp 57-58, 117. 5. Farnsworth, N.R., Akerele, O., Bingel, A.S. (1985). Medical Plants in Therapy. Bull. World Health Organization. 63:965-981. 6. Akerele, O. (1991). Medical Plants: Policies and Priorities. In Akerele, O., Heywood, V., and Synge, H. (Eds) Conservation of Medical Plants. Cambridge University Press, Cambridge. Pp 200-250. 7. Fellows, L.E. (1991). Pharmaceuticals from Traditional Medical Plants and Others: Future Prospects. A Paper Presented at the Symposium ‘New Drugs from Natural Source’. Sponsored by I.B.C. Technical Services Ltd. London. June 13th-14th 1991. Royal Botanical Gardens, Kew. 8. Farnsworth, N.R. and Soejarto, D.D. (1991).Global Importance of Medical Plants. In: Akerele, O., Heywood, V. and Synge, H. (Eds)Conservation of Medical Plants. Cambridge University Press, Cambridge. Pp 200-250. 9. Oliver, B.E.P. (1960). Medicinal Plants. Journal of Nigerian Field Society. 24(2):54-71. 10. Irvine, F.R. (1966). West African Botany. 2nd Edition Oxford University Press, London. 80pp. 11. Holland, J.H. (1922). Useful Plants of Nigeria. Bulletin of Miscellaneous Information. IX:19-21. 12. Singh, M.P., Malla, S.B., Rajbhandari, S.B. and Manadkar, A. (1980). Medical Plants of Nepal. Eco. Bot. 33(2)185-193. 13. Jain, S.K. and Borthakur, S.K. (1980). Ethnobotany of Mukurs of India. Eco. Bot. 34(3):268. 14. Egunjobi, J.C. (1978). Uses of West African Plants. Ibadan Oxford University Press. Pp 22-30. 15. Shiv, D.L. and Kamlesh, (1980). Plants used by the Bhat Community for Regulating Fertility. Eco. Bot. 34(3): 273-275. 16. Kumar, S., Shrukla, Y.N., Lavania, U.C., Sharma, A and Singh, A.K. (1997). Medicinal and Aromatic Plants: Prospects for India. J. Med. Arom. Pl.Sci. 19(2)361-365. 17. Joy, P.P., Thomas, J., Mathew, S., Skaria, B.P. (1998). Medical Plants, Kerala Agricultural University, Aromatic and Medicinal Plant Research Station. 18. Parfitt, R.T. (1978). Drug Discovery, Design or Serendipity. An Inaugural Lecture Series. University of Bath U.K. 19. Baqar, S.R., (2001). Anti-Spasmoslic Action of Crude Methanolic Extract. Journal of Medical Plants Res.Vol. 6(3) 461-464. 20. WHO (1978b). The Promotion and Development of Traditional Medicine. Technical Report Series 622. 21. Sofowora, A. (1993b), Medicinal Plants and Traditional Medicine in Africa (2nd Edition). Spectrum Books Ibadan Nigeria. Pp20-140. 22. Baba, S., Akerele, O. and Kawguchi, Y. (1992) Natural Resources and Human Health (Eds). Elsevier Tokyo. Pp 50-180. 23. Maxwell, N.C. (1962). Witch Doctor’s Apprentice. Victor Gollancz (Ed.) London. 353pp. 24. Bruneton, J (1995). Pharmacognosy, Phytochemistry and Medical Plants. Intercepts Ltd England UK. Pp 110-115. 25. Akerele, O (1988). Medical Plants and Primary Health Care: An Agenda for Action Fitoterapia Lix (5): 356. 26. Enwonwu, C.O. (2003). Global Trends in the Use of Complimentary Medicine. Proceedings of the 2nd Dr. David Barmes’ Memorial Public Health Symposium, 25th March 2003, Organised by the Regional Center for Oral Health Research and Training for Africa, Jos in Collaboration with WHO Regional Office, Brazzaville. 27. Wallis, T.E. (1967). Textbook of Pharmacognosy 5th Edition J&A Churchill Ltd. London. Pp.355. 28. Sofowora, A. (1993a). Recend Trends in Research into African Medicinal Plants. J.Ethropharmacolo. 38:209-214. 29. Lewis, E and Lewis, E. (1977). Medical Botany. John Wiley & Sons. New York. 515pp. 30. Bailey, C. J. and Day, C. (1989). Traditional Plant Medicines as Treatment for Diabetes. Diabetes care, 12 American Diabetes Association. Pp 553-564.

Ayurveda emphasizes on preventive aspects rather than curative. Ayurveda has got three fold management of all diseases viz., Ahara (diet), Vihara (exercise) and Aushada (drug). A properly selected diet and diet plan plays a critical importance in the management of any disease. There is a surge of oat cereal in market. Oat is a yavak, which is decribed under kudhanya varga in samhitas and nighantus. This papers reviews the botanical description of Jaii, its uses, action, pharmacological activities along with whole cultivation practices. REFERANCES 1. Handbook of Agriculture, 4th edition .Publised by DIPA (Directorate of information and Publication of Agricuture), ICAR,PUSA, New Delhi, 2008, 886-890 2. Bhavprakash ; Bhavprakash Nighantu, (commentary by Dr.K.C.Chunekar & Dr. G.S.Pandey), Chaukhambha Bharati Academy, Reprint 2002,667 3. Sushruta; Sushruta Samhita commentary by Ambika Dutt Shastri; Chaukhamba Sanskrit Sansthan, Reprint 2007, 68. 4. Ross. Ivan S; Medicinal Plants of the world,Chemical Constituents, Traditional and Modern Medicinal Uses, Vol 3, Humana Press; 2005 5. A. Vogel. Avena sativa L. Oats. A. Vogel Plant Encyclopaedia. [Online] http://www.avogel.ca/en/plant-encyclopaedia/avena_sativa.php. 6. Ben-erik-van-wyk; Food Plants of the World, ,1st edition, Briza publications, South Africa2005, 80 7. Misri,B., R.N.Choubey and S.K.Gupta, Performance of some new Oat strains for fodder production in Kashmir Himalaya. Oat Newsletter,1984, 35. 8. Encyclopedia of World Medicinal Plants, Volume 1, Regecy publications, 2006, 260 9. Katie M Queenan,Maria L Stewart,Kristen N Smith, William Thomas,R Gary Fulcher,and Joanne L Slavin , Concentrated oat β-glucan, a fermentable fiber, lowers serum cholesterol in hypercholesterolemic adults in a randomized controlled trial. www.pubmedcentral.nih.gov/fprender.fcgi 10. Czerwiński J, Bartnikowska E, Leontowicz H, Lange E, Leontowicz M, Katrich E, Trakhtenberg S, Gorinstein S., Oat (Avena sativa L.) and amaranth (Amaranthus hypochondriacus) meals positively affect plasma lipid profile in rats fed cholesterol-containing diets. Department of Physiology Science, Faculty of Veterinary Medicine, Warsaw Agricultural University, Nowoursynowska 159, 02-787 Warsaw, Poland. www.ncbi.nlm.nih.gov/pubmed 11. Connor J, Connor T, Marshall PB, Reid A, Turnbull MJ. J Pharm Pharmacol. The pharmacology of Avena sativa. 1975 Feb;27(2):92-8 // www.ncbi.nlm.nih.gov/pubmed 12. , Colleoni-Sirghie et al., Molecular Weight Distribution of (1→3)(1→4)-β-Glucan Affects Pasting Properties of Flour from Oat Lines with High and Typical Amounts of β-Glucan, 2003 http://www.aaccnet.org/cerealchemistry/freearticle/CCHEM-84-5-0471.pdf 13 Van Horn et al., 1988; Shinnick et al., 1991, Cholesterol lowering effects in Hamsters of β-glucan enriched barley fraction dehulled whole barley,ricebran and oat bran and their combinations.( http://www.aaccnet.org/cerealchemistry/backissues/1993/70_435.pdf.

The leading causes of mortality among aged people comprises of respiratory problems, heart diseases, cancer and stroke. Significant causes of morbidity among this group is chronic inflammatory and degenerative conditions such as Arthritis, Diabetes Osteoporosis, Alzheimer’s disease, depression, psychiatric disorders, Parkinson’s disease and age related urinary problems showing the paradigm shift of morbidity and mortality from communicable diseases to non-communicable one. The biggest challenge with geriatric diseases is that in most of the cases the condition cannot be attributed to a single cause or in certain conditions of neuro-psychiatric disorders like, Senile dementia, Alzheimer’s disease, depression, the structural cause is unknown. In such cases the conventional medical therapy fails to come out with effective management plan and hence is severely compromised. Another challenge with conventional medical therapy is that it does not have specific health-promoting agents. The word "yoga" comes from the Sanskrit root yuj, which means "to join" or "to yoke". Yoga is an ancient art based on a harmonizing system of development for the body, mind, and spirit. Patanjali’s famous definition of yoga is “yogas chitta vritti nirodhah”, which means “yoga is the controlling the fluctuations of the mind”. Chitta is mind, vrittis are thought impulses, nirodah is completely retraining. Yoga is method of channelizing energy through various physical and mental exercises. One can channelize his/her energy and can use it for fruitful purpose or destructive purpose. The paper will throw light on energy channelizing process through Yogic practices and its importance in combating geriatric diseases. REFERANCES United Nations. Report of the Second World Assembly on Aging. Madrid, Spain: United Nations, April 8--12, 2002. Kinsella K, Velkoff V. U.S. Census Bureau. An Aging World: 2001. Washington, DC: U.S. Government Printing Office, 2001; series P95/01-1. World Health Organization. World Health Report 2002, Annex Table 2 (deaths by cause, sex and mortality stratum in WHO Regions, estimates for 2001). Geneva, Switzerland: World Health Organization, 2002:186--91. 4. Baena-González E.Energy signaling in the regulation of gene expression during stress. Mol Plant. 2010 Mar;3(2):300-13. 5. Donnelly M, Scheffler IE. Energy metabolism in respiration-deficient and wild type Chinese hamster fibroblasts in culture. J Cell Physiol. 1976 Sep;89(1):39-51. 6. Saatcioglu Fahri .Regulation of gene expression by yoga, meditation and related practices: A review of recent studies.Asian Journal of Psychiatry. 2013; 6(1):pp 74-77. 7. Cain CE, Blekhman R, Marioni JC, Gilad Y.Gene expression differences among primates are associated with changes in a histone epigenetic modification. Genetics. 2011 Apr;187(4):1225-34. 8. Li QZ, Li P, Garcia GE, Johnson RJ, Feng L. Genomic profiling of neutrophil transcripts in Asian Qigong practitioners: a pilot study in gene regulation by mind-body interaction. J Altern Complement Med. 2005;11: 29–39. 9. Bierhaus A, Humpert PM, Nawroth PP.NF-kappaB as a molecular link between psychosocial stress and organ dysfunction. Pediatr Nephrol. 2004 Nov;19(11):1189-91. 10. Forsythe JA, Jiang BH, Iyer NV, Agani F, Leung SW, Koos RD, Semenza GL.Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol Cell Biol. 1996 Sep;16(9):4604-13. 11. Liu Y, Cox SR, Morita T, Kourembanas S. Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5' enhancer. Circ Res. 1995 Sep;77(3):638-43. 12. Holmes, Katherine; Roberts, Owain Ll; Thomas, Angharad M. "Vascular endothelial growth factor receptor-2: Structure, function, intracellular signalling and therapeutic inhibition". Cellular Signalling Cross, Michael J;2007. 19 (10): 2003–12. Akeno N, Czyzyk Krzeska MF, Gross TS, Clemens TL. Hypoxia induces vascular endothelial growth factor gene transcription in human osteoblast-like cells through the hypoxia-inducible factor-2alpha. Endocrinology.2001; 142: 959-962..

B.diffusa (Punarnava) is an available and well known herb all over the world. It is traditionally use and popular for various purposes because of its potential action. It is use in fever, edema, anemia, jaundice, spleenomegaly, menstrual disorder, sexually transmitted diseases etc. It has potent rejuvenator property. Its chemical constituents effective against a large number of ailments, resent research proved that. This article is try to provide the basic information about this herb, found in Ayurvedic text as well as resent research. REFERANCES 1. Sastri J.L.N, Drabya Guna Vijnana. Chaukhambha orientalia ,Varanasi, 3rd Edition 2008,3rd vol, p-437-441. 2. Mishra S, Bhavaprokash (Hindi commentary), Chaukhambha Sanskrit Bhawan, Varanasi, 11th Edition 2010, 1st part, p-426- 428. 3. Sharma P.V, Drabya Guna Vijnana. Chaukhambha Bharati Academy, Varanasi, 3rd Edition 1999,2nd vol, p-360. 4. ChatterjeeA, Pakrashi S.C. The Treaties on Indiana Medicinal Plant, CCIR, New Delhi 110012; 1st Edition, 1st Vol, 1991,p-76. 5. Sharma P.C. et al, Data base on Medicinal Plants used in Ayurveda, Central Council for Research in Ayurveda & Siddha, New Delhi, 2001 ,1st Vol, p-264. 6. Hiruma Lima K, Database entry for Erva tostao B, diffusa,White house, 1996;32:4-45. 7. Mehrotra M.and Bharalli H, Haematinic property of B.diffusa Linn. Extract, Research in Science and technology. 2001;3(7):04-07. 8. Sreeja S and Sreeja S, an in vivo study on Anti proliferative and anti estrogenic Effect of B.diffusa L, extracts. Journal of Ethno pharmacology, 1923; 126:221-225. 9. Nalamola M, Orisakwa OE,Hypoglycaemic Effect of the aqueous extract of B.diffusa leave, Indian Journal of Phermacology, 2001, 33(3); 205-216. 10. Chopra N and Naddkarni A.KL, Indian Meteria Medica , Popular prokashon, Bombey,1994, 2nd Edition,Vol-1. 11. Agaewal A and Dutta S. Effect of B.diffusa in target fungal species, Indian Journal of Pharmacology ;1986,28:161-165. 12. Srivastava P, Fribinolytic activity of freeze dried ethonolic extract of B.diffusa. Indian Journal of Pharmacology, 1989; 44(3):121-128. 13. Awasthi G,and Menzel K, Anti Viral Activity of B.diffusa root extract on RNA Containing bacterial viruses.1986;12:21-38. 14. Rai P.Upadhyay SK , In vitro anti fungal activity against M.nanumi. Indian J Phermacology , 2012; 44(3):345-356 15. Chandan D, Cholerecti Activity of B.diffusa ethanolic extract induced by carbon tetrachloride in mice.1990; 31(6):829-835. 16. Singh SP,Diwedi K.and Roy S, Teratogenic effect of B.diffusa ethanolic extract in fetus rat, Indian J Clin ,1991 ;22(8): 387-391. 17. Singh KK, Anaad P,Department of pharmacology ,Regional Research Laboretory, Canal Road , Jammu ,1992;12: 60-67. 18. Murthy G Prokash, Hepatoprotective activity of aqueous extract of B.diffusa root,1 992, 4(3):184-188. 19. Pandey S,Sharma P, Selective Immunosuppressive activity of leaf extract of B,diffusa (L).2004 ; 12(8): 51-55. 20. Borrelli W, Effect of B .diffusa extract on smooth muscles ,Neuroci Today, 2009;12 :13-21. 21. Manu G,and Kuttan O,B.diffusa root extract increases host defence ,Med update.2007:26(4):1-8. 22. Paramanic P, Priya J,and Suriyavathana M, Evalution of Anti oxidant Potential of Andrographis echiodes and B .diffusa, International Journal of current Research ,2007;3:59- 62. 23. Somanth TK, Mustaffa G, In-vitro Anti oxidant property of root of B .diffusa Linn. Research Journal of Pharmaceutical Biological and Chemical Science , 2010;1(4):782-788. 24. Velmurugan De Keille,and Heshwara Unama ,Indian Herbs with anti Bacterialproperty. Fitotepia , 2010;64(1):42-44. 25. Agaewal A and Dutta S. Effect of B.diffusa in target fungal species, Indian Journal ofPharmacology ,2004;28:161- 165. 26. Chopra, Ghosh and De, Indian Meditional Gazette.2002; 31:122-124. 27. Sharma P.V, Ayurveda ka vaijnanika itihas,. Chaukhambha orientalia, Varanasi,4th Edition (1999), p-46. 28. Agnivesha, Caraka Samhita, Elaborated by Charaka and Dridabalal. English Commentary by Acharya R.K.Sharma and Bhagwan Das, Chaukhamba Sanskrit series office, Varanasi , 2007.Vol-1,Sutra sthan, 4th chapter, sloka –12 -18.p-93-101. 29.Maharshi Sushruta , Sushruta Samhita, English Commentary by Prof K.R. Srikantha Murthy, Chaukhamba orientalia,Varanasi, reprint2010, vol-1, Sutrasthan -,chapter38 ,sloka-,4 pp-265. 30. Acharya vagbhatta, Astanga Hridaya, English Commentary by Prof K.R. Srikantha Murthy, Krishna Das Academy, Varanasi,9th Edition, 2013.vol 1, Sutrasthan, 4th chapter,sloka169, p-107. 31. P.V.Sharma, Dhanwantari Nighantu. Chaukhambha orientalia, Varanasi, 1st Edition, 1982.p65. 32. Madan Pal Nripa, Madan pal Nighantu(Hindi), Ganga Vishnu Srikrishnadas Press, Bombey; Edition 1954. 33. Shree Krishna Sastri GB, Madanpal Nighantau . Chaukhambha Bharati Academy ,Varanasi 1st Edition, 1954, p-34. 34. Shree Krishna Das Sastri, Saligram Nighantau, Bhusanam, Mumbai,1st Edition, 1980, p-319-322. 35.Pt. Narahori , Raj Nighantu ,Edited by I. Tripathi , Krishna Das Academy, Varanasi, 2nd Edition 1998, p-127-129. 36.P. Sharma , Priya Nighantu. Chaukhambha orientalia, Varanasi, 1st Edition( 1983), P-104. 37B.G. Vaidya , Nighantu Adarsa(uttardha). Chaukhambha orientalia, Varanasi, 1st Edition( 1985).p-263-269. 38. Acharya Jadavji Tricamji, Dravyaguna Vijana, Sharma Ayurveda Mandir; 3rd Edition,1978. 39. P. Narahori , Raj Nighantu ,Edited by I. Tripathi , Krishna Das Academy, Varanasi, 2nd Edition , 1998, p-127-129. 40. J.L.N.Sastri , Drabya Guna Vijnana. Chaukhambha orientalia ,Varanasi, 3rd Edition 2008,3rd vol, p-437-441. 41.S. Mishra ,Bhavaprokash (Hindi), Chaukhambha Sanskrit Bhawan, Varanasi, 11th Edition 2010, 1st part, p-426- 428. 42.P. 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Background & Objectives: - Because of increasing life expectancy and falling death rate, the population of world is becoming older. The number of aged persons increased and Geriatrics complaint like dementia, MCI, Alzheimer’s demands more medical attention. Changes in cognitive abilities are part of normal ageing process. There are of course individual differences in the age at which cognitive state begins to decline as well as in the rate at which these losses takes place. Understanding the genetic make up of an individual is the key to personalized therapy.Hence it becomes necessary to categorize individuals on the basis of broad phenotypic clusters. Prakriti has genetic connotation that could provide a tool for classifying human population based on broad phenotype. So now at this moment this study is carried out to evaluate the cognitive functions in different Prakritis with respect to ageing and to analyze and interpret the study results with modern medicine and Ayurveda perspective to formulate useful guideline. REFERANCES 1) Ageing and neuronal vulnerability Mark P. Mattson*‡ and Tim Magnus* Nature Reviews | Neuroscience Volume 7 | April 2006 | 2) Bhushan, P. et al. (2005). Classification of human population based on HLA gene polymorphism and the concept of Prakriti in Ayurveda. J. Alt. Compl. Med. 10:879-889. 3) Charaka Samhita Vimana Sthana, 8/96,97,98 4) Sushruta Samhita Sareera Sthana, 4/64-67,68-71,72-76 5) Astanga Sangraha Sareera Sthana, 3/84-89.,90-95,96-102 6) Folstein MF, Folstein SE, McHugh PR: “Mini-mental state: A practical method for grading the cognitive state of patients for the clinician.” J Psychiatr Res 1975;12:189-198. 7) Patwardhan, Bhushan & Joshi, Kalpana (2009, January 23). Ayurvedic Genomics: Integration for Customized Medicine 8) Sushruta; Sushruta Samhita, Ayurveda Tattva Sandipika by Kaviraj Ambikadatta Shastri, Chaukhambha Sanskrit Samsthan, Varanasi 20th edition, 2001sutrasthana35/29-31 1.

REFERANCES 1. Duarte IDG, Nakamura M, Ferreira SH. Participation of the sympathetic system in acetic acid induced writhing in mice. Brazilian Journal of Medicine and Biological Research. 1988; 21:341-343. 2. Sabina EP, Chandel S, Rasool MK. Evaluation of analgesic, antipyretic and ulcerogenic effect of Withaferin A. International Journal of Integrative Biology. 2009; 6(2):52-56. 3. Alhaider AA, Lei SZ, Wilcox GL. Spinal 5-HT mediated anti-nociception: Possible release of GABA. J Neurosci. 1991;11(7):1881-8. 4. Ibironke GF, Ajiboye KI. Studies on the anti-inflammatory and analgesic properties of Chenopodium ambrosioides leaf extract in rats. International Journal of Pharmacology. 2007;3(1):111-115. 5. Elisabetsky E, Amador TA, Albuquerque RR, Nunes DS, Cavalho ACT. Analgesic activity of psychotria colorata (Wild ex R and S). muell arg. Alkaloids. Journal of Ethnopharmacology. 1995;48(2):77-83. 6. Pal S, Sen T, Chaudhuri AK. Neuropsychopharmacological profile of the methanolic fraction of Bryophyllum pinnatum leaf extract. Journal of Pharmacy and Pharmacology. 1999;51:313-318. 7. Tjolsen A, Berge OG, Hunskaar S, Rosland JH, Hole K. The formalin test: an evaluation of the method. Pain. 1992;51(1):5-17. 8. Pathmanathan MK, Uthayarasa K, Jeyadevan JP. In Vitro antibacterial activity and phytochemical analysis of some selected medicinal plants. International Journal of Pharmaceutical and Biological Archives. 2010;1(3):291–299.

Sandhigata vata is described under Vatavyadhi in Ayurvedic texts. It can be correlated with Osteoarthritis in modern science. Osteoarthritis is also known as degenerative arthritis that results from breakdown of joint cartilage. Its prevalence is more in female and among old age people. It mainly affected weight bearing joints of the body specially knee, hip, lumbar spine associated with ageing, physical occupation, activity and obesity. In Ayurveda symptom of sandhigatavata are sandhishula, sandhishotha, akunchna prasarna janya vedna and hanti sandhigati described by various acharya. In the present study the diagnosed cases of sandhigata vata were treated with convestional Ayurvedic oral medicines alongwith local application of medicated oil and patra panda potali swedana as a special therapy. The result showed that Ayurvedic treatment procedures are significant in the sandhigata vata without any ADR. The result of present study revealed the therapeutic use of natural product according to Ayurvedic principal and practice of Sandhigata vata. The improvement of the present Ayurvedic treatment procedure on pain 61.90%, stiffness 69.44%, restricted movement 63.15%, crepitating movement 56.66% and tenderness73.33%. The overall relief was observed 64.89%. REFERANCES 1 Bhavaprakasha of Bhavamishra, English translated by Prof. K.R. Srikanta Murthy Vol. 2, part II page no -348 2. Susruta Samhita Nidana Sthana, English translation edited by Priyavrat Sharma ,Vol. II, Chaukhamba Bharati Academy 1st edition 2002, page no -8. 3. Charaka Samhita , Chikitsa Sthana, English translation based on Chakrapani dutta and Ayurveda Dipika by R. K. Sharma, Bhgwan Dash Chowkhamba Sanskrit Series, Varansi edition 2012,page 29 . 4. Davidson medicine , edited by Brian R walker, Nicki R, Colledge, Stuart H ,Ralston, Ian D Penmon , 22nd edition , page No 1081 5. Obstetric & Gynecologic diagnosis and treatment edited by Alan H .Decherney & martin L Pernoll 18 edition page no-1036 6. Susruta Samhita Chikitsa Sthana , English translation of text Vol. II edited by Priyavrat Sharma , Chaukhamba Bharati academy 1st edition 2002,page no -305. 7.Astanga samgrah of Vagbhatta , Chikitsa Sthana, English translation by K R srikanta Murty , Chaukhamba Orientallia , Varanasi page no-523 8.Panchkarma applied aspect, Vaidyaratna Ayurveda Foundation , Thaikkattussery , Thrissur , Kerala 2010 page no 96-97 9.Madhava Nidanam with commentaries the Madhukosha of Srivijayarakshita and Shrikanthadutta, Hindi commentary edited by Dr. Brahmananda Tripathi , Chaukhamba Surbharati Prakashana , Varanasi 1st edition 1996, page no- 39. 10.The Ayurvedic Pharmacopoeia of India , part-1 vol. I , 1st edition , Govt of India page no-16 & 104. 11. The Ayurvedic Formulary of India, Part I ,2nd revised edition , Govt of India ,2003, page no-132.

Ayurveda has emerged as a new hope for the world in terms of its usefulness in treating various diseases with minimal adverse effects. The holistic approach towards health and disease is the major strength of this science. It has gained a lot of acceptance and appreciation around the globe. To meet the expectations of the scientific community at every level, it is important that the system is explained to the modern world in the language and the terminology they understand. At the same time, if anatomy and physiology of excretory system is clear, it will be helpful for the Ayurvedic physicians to understand the pathological conditions of this system of the body and their effective treatment. Ayurveda has presented a very brief description about the structure and function of the excretory system. It has only mentioned the existence of the structures which may be responsible for functions of excretion. This article is an effort to explain the anatomy of excretory system explained in Ayurvedic texts in view of modern day knowledge. REFERANCES 1. Sheshayyan S., Inderbir Singh’s textbook of anatomy, ed. 6, 2016, The Health Science publisher, New Delhi, Vol II., 259. 2. Hargobind Shastri, Amarkosha of Amarsingh, Edn 2nd, Chaukhambha Sanskrit Sansthan, Varanasi, 1982, 243. 3. Sushruta Samhita, Nibandhasamgraha commentary of Dalhana, Nyayachandrika commentary of Gayadasa, edited by Yadavji Trikamjee Acharya and Narayan Ram Acharya, Chaukhamba Orientalia, Varanasi, Reprint 2009, p. 386. 4. Shukl V, Tripathi R D, Charak Samhita of Agnivesha Edn 2, Part I, Chaukhambha Sanskrit Pratishthan, Varanasi, 2000, 766. 5. Ambikaduttshahtri , Susruta Samhita of Maharishi Sushruta, Sharirsthan, Edn 12, Part-I, Chaukhambha Sanskrit Sansthan, Varanasi, 2001, 41. 6. Shrikantha Murthy KR. Ashtang Samgrah of Vagbhatta. Vol. II. Edi. 4th. Chaukhamba Orientalia, Varanasi, 2003; 65. 7. Sushruta Samhita, Nibandhasamgraha commentary of Dalhana, Nyayachandrika commentary of Gayadasa, edited by Yadavji Trikamjee Acharya and Narayan Ram Acharya, Chaukhamba Orientalia, Varanasi, Reprint 2009, 303. 8. Sushruta Samhita, Nibandhasamgraha commentary of Dalhana, Nyayachandrika commentary of Gayadasa, edited by Yadavji Trikamjee Acharya and Narayan Ram Acharya, Chaukhamba Orientalia, Varanasi, Reprint 2009, 358. 9. Shukl V, Tripathi R D, Charak Samhita of Agnivesha Edn 2, Part I, Chaukhambha Sanskrit Pratishthan, Varanasi, 2000, 270. 10. Ambikaduttshahtri , Susruta Samhita of Maharishi Sushruta, Sharirsthan, Edn 12, Part-I, Chaukhambha Sanskrit Sansthan, Varanasi, 2001, 72. 11. Shastri Durgadutta, Sharangdhara Samhita, Chaukhambha Vidyabhawan, Varanasi, Reprint 2002; 68. 12. Sheshayyan S., Inderbir Singh’s textbook of anatomy, ed. 6, 2016, The Health Science publisher, New Delhi, Vol II., 268. 13. Guyton AC and Hall JE. Text Book of Medical Physiology. Edi. 9th. W. B. Saunders Company, Philadelphia. 1996: 963. 14. Guyton AC and Hall JE. Text Book of Medical Physiology. Edi. 9th. W. B. Saunders Company, Philadelphia. 1996: 968. 15. Standring S. Grey’s Anatomy. Edi. 40th. Elsevier. 2008: 1226. 16. Sushruta Samhita, Nibandhasamgraha commentary of Dalhana, Nyayachandrika commentary of Gayadasa, edited by Yadavji Trikamjee Acharya and Narayan Ram Acharya, Chaukhamba Orientalia, Varanasi, Reprint 2009, 279. 17. Guyton AC and Hall JE. Text Book of Medical Physiology. Edi. 9th. W. B. Saunders Company, Philadelphia. 1996: 317. 18. Ambikaduttshahtri , Susruta Samhita of Maharishi Sushruta, Nidansthan, Edn 12, Part-I, Chaukhambha Sanskrit Sansthan, Varanasi, 2001, 242. 19. Krishna Garg. BD Chaurasia’s Human Anatomy. Reprint Edi. 5th. CBS publishers & Distributors Pvt Ltd. New Delhi. 2012. 375. 20. Ambikaduttshahtri , Susruta Samhita of Maharishi Sushruta, Sharirsthan, Edn 12, Part-I, Chaukhambha Sanskrit Sansthan, Varanasi, 2001, 42. 21. Standring S. Grey’s Anatomy. Edi. 40th. Elsevier. 2008: 1245. 22. Sheshayyan S., Inderbir Singh’s textbook of anatomy, Edition. 6th, 2016, The Health Science publisher, New Delhi, Vol II., 307. 23. Standring S. Grey’s Anatomy. Edi. 40th. Elsevier. 2008: 1245 24. Krishna Garg. BD Chaurasia’s Human Anatomy. Reprint Edi. 5th. CBS publishers & Distributors Pvt Ltd. New Delhi. 2012. 377. 25. Sheshayyan S., Inderbir Singh’s textbook of anatomy, Edition. 6th, 2016, The Health Science publisher, New Delhi, Vol II., 311.

Prameha (Diabetes Mellitus)a metabolic disorder is one of the Asthamahagada. Various drugs and formulations have been explained in the text for the treatment of prameha depending upon the involvement of the dosh and dushyas. Nishamalaki is one of the effective formulations explained in astangahradaya for the management of Prameha. The concept of samaskara has been explained in caraka samhiavimanashana for the transmigration of gunas better therapeutic effect of the drugs. In the present study effect of bhavana samskara on physico-chemical and phytochemical characters of nishamalaki formulations developed at pharmacy of Sri Jayendra Saraswathi Ayurveda College, Chennai. . The nishamalki formulation was prepared by mixing the Nisha (Curcuma longa) and Amalaki (Emblica officinalis) powders in equal proportions. The mixture was triturated with juice of Amalaki for three days. Nishamalaki powder without any treatment with juice was considered as control. Organoleptic, microscopic, phytochemical and levels of Vit C and curcumin was estimated. Among the physico-chemical characters, the formulations following samaskara showed increased levels of total ash, water soluble ashand yield of alcoholic extract while other parameters showed no significant change. Nishamalaki following samskara showed the presence of proteins, carbohydrates, phenol, tannin and flavanoids in the aqueous extract while alcoholic extract showed the presence of proteins, carbohydrates, tannin, flavanoids, glycosides, steroids, terpenoids and alkaloids. In control formulation phenols, tannins and favanoids were present in aqueous extract while proteins, carbohydrates, phenols and tannins were present in alcoholic extract. A significant difference in Vit C and curcumin levels were observed following samskara of nishamalaki. Observed improvement in the active constitutes following bhavana samaskara confirms the scientific basis behind methods and procedures suggested in preparation of ayurvedic formulations. REFERANCES 1.Sastri K. (2006),edited by Dr. Gangasahaya Pandeya, Caraka Samhita, Vimanasthana 1/22,Chaukambha Sanskrit Sansthan, Varanasi 2.Kaviraja Atrideva Gupta, edited by Vaidya Yadunadana Upadhyaya, Astanga Hradaya, Prameha Chikitsasthana 12/5, Chaukambha Sanskrit Sansthan, Varanasi; 372. 3. Edward C.R.W, Bouchier I.A.P, Haslett C., Davidson Principles of Medicine; 1990. 724. 4. Sastri, K.A, Susruta Samhita Sutrasthana. 46/144, Chaukambha Sanskrit Sansthan, Varanasi; 2012. 256. 5. Chunekar K.C, edited by G.S. Pandey, Bhavaprakasha Nighantu, Chaukambha Bharati Academy, Varanasi; 1995 6. Narahari, edited by Indradeo Tripathi, Raja Nighantu, Karaveeradi Varga Krishnadas Academy, Varanasi; 1998. 371. 7. Chunekar K.C, edited by G.S.Pandey, Bhavaprakasha Nighantu, Chaukambha Bharati Academy, Varanasi; 1995. 132. 8. Sastri K.V,Susruta Samhita Sutrasthana 46/144,Chaukambha Sanskrit Sansthan, Varanasi; 2012. 256. 9. Satry J.L. Illustrated Dravya Guna Vigyan Vol 2,ChaukambhaOrientalia, Varanasi; 2014.220. 10.Chunekar K.C, edited by Dr.G.S.Pandey, Bhavaprakasha Nighantu, Chaukambha Bharati Academy, Varanasi; 1995. 132. 11.Chunekar K.C, edited by G.S.Pandey, Bhavaprakasha Nighantu, Chaukambha Bharati Academy, Varanasi; 1995.132. 12.Chunekar K.C, edited by G.S.Pandey, Bhavaprakasha Nighantu, Chaukambha Bharati Academy, Varanasi; 1995.132. 13.Sastri K.A,Susruta Samhita Sutrasthana 46/144,Chaukambha Sanskrit Sansthan, Varanasi; 2012. 256. 14.SatryJ.L,Illustrated Dravya Guna Vigyan, Vol 2, Chaukambha Orientalia, Varanasi; 2014. 513. 15.Trease E.G, Evans W.C, Pharmacognosy.11thed. Bailliere Tindall, London; 1978.115. 16. Ayurvedic Pharmacopeia of India, Ministry of Health andFamily Welfare.New Delhi; 1996. 17. Kapur A, Haskovic A, Copra-Janicijevic A, Klepo L, TopcagicTahirovic I, Sofic E,. (2012). Spectrophotometric analysis of total ascorbic acid content in various fruits and vegetables. Bulletin of the Chemists and Technologists of Bosnia and Herzegovina, 2012; 40; 40-44.

The people of Baksa district of Western part of Assam frequently use some traditional medicine for minor bodily disorder. They have lot of experiences regarding herbal treatment of diseases like fever, intestinal worm, jaundice, cold and cough, head ache and many more. Here in this paper an attempt has been made to analyze data regarding treatment of nail or toe disorder. For this data were collected using a questionnaire and meeting the experienced knowledgeable persons in such traditional practices. The Plant items were collected in the presence of each particular healer who provided a particular recipe. Here four very simple recipes are mentioned. This disorder through not considered as a dangerous disease still a patient has to suffer a lot in severe case. Even the patient feels problem in walking, suffering from fever etc. But by following certain local health traditional practices one can get rid of this type of disorder before reaching severe condition. REFERANCES 1. Chowdhury, S :2005. Assam’s Flora, ASTEC (Assam), 2. Jain, SK & Rao, RR.:1997 A Handbook of filed and Herbarium methods. Today & Tomorrow’s printers and Publishers, New Delhi 3. Kanjilal, UN, P.C. Das and Purakaystha, 1934. Flora of Assam, Vol-I, Bishen Singh Mohendra Pal Singh, Dehradun, 4. Sharma. TP, S. Dahal & S.K Barthakur, Documentation of Ethno veterinary practices in Sikkim, India; Pleione 6 (2): 353- 358, 2012 5. Shoran S. 2011:Medicinal Plants. Pacific Books International. Kalyan Vihar (India). Statistical Hand Book of Assam 2014. Govt. of Assam

Herbal medicine has been practiced for centuries in many countries butthe legalityof herbal medicines varies from country to country. In certain countries herbal medicines are well-established, but they are not used under legal claim instead they are regarded under food and therapeutic claim. Developing countries, however, often have a great number of traditionally used herbal medicines and much folk-knowledge about them, but have hardly any legislative criteria to establish these traditionally used herbal medicines as part of the drug legislation. The herbal medicine sector is in a dilemma. Some practitioners would like to continue to practice as they do now, with no further regulation, and accept that their practice is based on tradition and personal experience rather than empirical science. The logical consequence of adopting this form of practice is that we should take a precautionary approach in order to ensure public safety. This article presentsoverview of regulatory challenges of herbal medicine in world and regulation, types of documents for herbal medicine in Russia.This work clearly gives the overview of the herbal drug registration requirements in Russia and also about the marketing authorization procedure and timelines involve. REFERANCES 1. Standardization of herbal medicines. Available at http://www.academicjournals.org/article/article1380017716_Kunle%20et%20al.pdf 2. Regulatory situation of herbal medicines. Available at http://www.dcscience.net/Report_on_Regulation_of_Herbal_Medicines_and_Practitioners.pdf 3. Report on the regulation of herbal medicines and practitioners. 4. The Safety of Herbal Medicine: From Prejudice to Evidence. Available at http://www.hindawi.com/journals/ecam/2015/316706/ 5. Current Scientific Status and Regulatory Control of Herbal medicine. Available at http://www.ijrap.net/admin/php/uploads/639_pdf.pdf 6. Regulatory issues of herbal medicine. Available at www.clininvent.com/.../Regulatory%20issues%20for%20tradintionl%2 7. Regulatory situation of herbal medicine worldwide. Available at http://apps.who.int/medicinedocs/pdf/whozip57e/whozip57e.pdf 8. WHO guideline on safety monitoring. Available at apps.who.int/medicinedocs/documents/s7148e/s7148e.pdf 9. Guidelines for the Appropriate use of Herbal Medicines. Available at apps.who.int/medicinedocs/en/d/Jh2945e/11.html 10. Framework for overcoming barriers of complementary and alternative medicine acceptance into conventional healthcare system. Available at http://www.academia.edu/5116752/Framework_for_overcoming_barriers_of_complementary_and_alternative_medicine_acceptance_into_conventional_healthcare_system 11. Pharmacovigilance of Herbal Products. Available at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159283/ 12. Pharmacovigilance of Herbal Products in India. Available at https://www.researchgate.net/publication/51620397_Pharmacovigilance_of_Herbal_Products_in_India 13. Regulatory framework for federal service for surveillance in healthcare. Available at http://www.roszdravnadzor.ru/en 14. Russian Federation Federal Law On Circulation of Medicines 61-FZ (EN).Available at https://www.unodc.org/res/cld/document/rus/federal-law-on-circulation-of medicines_html/Russian_Federation_Federal_Law_On_Circulation_of_Medicines_61-FZ_EN.pdf 15. Medicinal Plants of the Russian Pharmacopoeia; their history and applications. Available at http://www.sciencedirect.com/science/article/pii/S0378874114002827 16. European view on current regulatory legislation in the CIS countries. Available at http://dgra.de/media/pdf/studium/masterthesis/master_dranov_a.pdf 17. Regulatory framework for federal service for surveillance in healthcare. Available at http://www.roszdravnadzor.ru/en 18. Russia. Functions. Federal service on surveillance in healthcare and social development of Russian federation. Roszdravnadzor. Russia. Ministry of Health; 2007. [Cited 2012 Dec 15]. Available from: http://www.roszdravnadzor.ru/i/upload/files/1188395609.65833-4011.pdf 19. Alyona C. Registration of Pharmaceutical products in Russia. Pharmareg. [Internet] [Cited 2015 Jan 25]. Available from: http://pharmareg.ru/upload/ReportAChorichFrankfurt.pdf 20. Regulation of Herbal Medicinal Products in Russia. Available at https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0032-1307488 21. States registration of herbal drug in Russia. Available at http://www.msp.ua/registration-medicinal-products-russia.html 22. Docs for registration in Russia _for medical. Available at http://www.china-canny.com/html/fqabv.html 23. Satyanarayan, Shanta. "Full Scale Treatment of Herbal Pharmaceutical Industry Wastewater." [Internet] [Cited 2014 Nov 15] Available at http://www.ijcps.org/sp1/p7.pdf 24. National Policy on Traditional Medicine and Regulation of Herbal Medicines- Report on WWHO global survey. [Internet]. [Cited 2014 Nov 15]Available at http://apps.who.int/medicinedocs/en/d/Js7916e/9.4.html http://globalresearchonline.net/journalcontents/v31-1/30.pdf