Volume 6, Issue 4

Ayurveda provide unique treatment modalities and medicaments for the disease conditions. In Charaka Samhita classifications of drugs are made based on Karmas (actions) called asMahakashayaa Dashemani (group of ten drugs) and these are classified into 50 groups. Varnya Dashemani(group of complexion enhancing drugs) is one such group which is said to be more effective in curing the aliments related with skin complexion. In the present study a case of Topical steroid-dependent face - Acne rosaceawas administered with VarnyaMahakashayaGhanavati (250mg 4 tabs /BD) and VarnyaMahakashayachurna(powder) for 15 days and the formulation has provided significant relief in symptoms. Hence it can be considered that VarnyaMahakashayadrugs can be useful in treating Acne rosacea and can be taken for further clinical trials. References 1. 1. Acharya YT, editor. (5th ed.) Charaka Samhita. Sutra Sthana; Shadvirechanashatashriteeya: Chapter 4, Verse 10 (8). Varanasi: Chaukhambha Sanskrit Sansthan; 2006; 32. 2. Acharya YT, editor. (5thed.). Commentary Ayurveda Dipika of Chakrapanidatta on Charaka Samhita. Sutra Sthana; Shadvirechanashatashriteeya: Chapter 4, Verse 3. Varanasi: Chaukhambha Sanskrit Sansthan; 2006; 30. 3. Pallavi .G: A Study on the concept of Varṇya vis-à-vis clinical evaluation of efficacy of Varṇya gaṇa lepa inVyaṅga; GAMC, Mysore, 2012. 4. Rosacea. (2016, July 13). In Wikipedia, the Free Encyclopedia. (cited 2016 Jul 14) Available from https://en.wikipedia.org/w/index.php?title=Rosacea&oldid=729668060 5. P. R. Waratenne, Mahendra Prasad and M. S. Meena. The role of Varnya Maha Kashya in the maintenance of skin complexion. Anaplastology an open access journal. Cosmetology-2012, vol.1, issue.3, pp.77, 2012 [International Conference and Exhibition on Cosmetology & Cosmetics. Hyderabad International Convention Centre, India, 2012] 6. Sapna Narasanagi, Sujnana VS, Jyoti Devangamath, Shreevathsa. Hepatoprotective property of varnya mahakashaya – An innovative insight. Global J Res. Med. Plants & Indigen. Med. 2015; 4(8):172–181.

The aim of present study to investigated medicinal plants and documented the medicinal uses. The medicinal purpose information collected from traditional healers of Southern Western Ghats of Virudhunagar district, Tamil Nadu, India.. The present study reported 51 medicinal plants belonging to 37 families. In this study most dominant families were Fabaceae, Liliaceae and Lamiaceae. Leaves and roots were the most frequently used plant part for treatment diseases by traditional healers. The study was considered useful information offer to ethnomedicinal researcher, pharmaceutical industries and developing the conservation of important medicinal plants. References 1. 1. Adebayo-Tayo, BC, Adegoke AA, Okoh AI, Ajibesin KK. Rationalizing some medicinal plants used in the treatments of skin diseases. Afr. J. Microbiol. Res., 2010; 10:958-963. 2. WHO. Traditional Medicine, Fact Sheet: http:/www.who.int/mediacentre/ factsheets/fs134/en/ (Accessed on: 12.12.2015). 3. Haidar Ali, Ansaria KK. Indu Tripathib Medico- Ethnozoological Informations of Invertebrate Animals used by Tharu Tribes of Devipatan Division of Uttar Pradesh, India. The Journal of Ethnobiology and Traditional Medicine. Photon,2013;118: 402-409. 4. Addo V. Herbal medicines: socio-demographic characteristics and pattern of use by patients in atertiary obstetrics and gynaecology unit. J. Sci. Technol, 2008; 27:149-155. 5, Shukla, RS, Chandel PS. Plant ecology including ethnobotany and soil science. 3rd Edition Chand and Company New Delhi, 1972: 411. 6. Colette VH, Ben N. Common disease in Africa: an illustrated guide. 2nd Edition Netherland Press, 2001:1-85. 7. Pascaline J, Catherine L c, George O, Dennis, Charles M. An ethnobotanical study of medicinal plants used by the Nandi people in Kenya. J. Ethnopharmacol , 2008;116:370–376. 8. Prabhu S, Vijayakumar S, Morvin Yabesh JE, Ravichandran K, Sakthivel B. Documentation and quantitative analysis of the local knowledge on medicinal plants in Kalrayan hills of Villupuram district, Tamil Nadu, India, J. Ethnopharmacol, 2014; 157:7-20. 9. Parthiban R, Vijayakumar S, Prabhu S, Morvin Yabesh JE. Quantitative traditional knowledge of medicinal plants used to treat livestock diseases from Kudavasal taluk of Thiruvarur district, Tamil Nadu, India, J. Rev. Bras. De Farmacog, 2016; 26:109-121. 10. Vijayakumar S, Morvin Yabesh JE, Prabhu S, Ayyanar M, Damodaran R. Ethnozoological study of animals used by traditional healers in Silent Valley of Kerala, India, J. Ethnopharmacol. 162 (2015) 296-305. 11. Giday M, Asfaw Z, Woldu, Z. Ethno medicinal study of plants used by Shekoethnic group of Ethiopia, J. Ethnophar, 2010; 132:75-85.

Infertility (Clomiphene) is defines as a failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse. Reasons such as weight, diet, smoking, medical conditions, other substance abuse, environmental pollutants, medications and family medical history, infections might have an effect on conception in couples. Infertility can arise from either of the partners. Infertility is usually because of low numbers or poor quality of sperm in men whereas in woman, it occurs when she is not able to produce eggs regularly or because her fallopian tubes are damaged or blocked and the sperm cannot reach her eggs. This article presents infertility from the lens of Ayurveda, discussing the ayurvedic concepts and practices that are followed in case of infertility in females. References 1. Sharma PV. Charaka-Samhita. Agnivesha’s Treatise, Refined and Annotated by Charaka and Redacted by Dridhabala, Vol II., (Chaukhambha Orientalia, Varanasi, 1981-1994), Chapter XXX, Page 502, Verses 1-40. 2. Prof. K.R. Srikantha Murthy, Astanga Hrdayam Volume 3 (Krishnadas Ayurveda Series, 2010), Chapter 4. 3. Sushruta Samhita-KL Bhishagratna Translator (Chaukhamba Orientalia, Varanasi, India, 1991), Pages 3-23 (I), 45-49 (II). 4. Sharma PV. Charaka-Samhita. Agnivesha’s Treatise, Refined and Annotated by Charaka and Redacted by Dridhabala, Vol I., (Chaukhambha Orientalia, Varanasi, 1981-1994), Chapter 1, Page 6, Verse 42. 5. Dr. David Frawley, Dr. Subhash Ranade, Ayurveda – Nature’s Medicine (Lotus Press, 2001), Pages 3-7. 6. David Frawley, Yoga and Ayurveda, (Lotus Press, Twin Lakes, Wisconsin, 2000): Pages: 112-115. 7. Maya Tiwari, Women’s Power to Heal through Inner Medicine (Mother OM Media, 2007), Chapters 1-5. 8. Dr. Marc Halpern, Textbook of Clinical Ayurvedic Medicine, (Sixth Edition), Second Volume (Grass Valley: California College of Ayurveda, 2008), Pages 5-7. 9. The Merck Manual of Medical Information, Merck Research Laboratories, a Division of Merck and Co., Inc., (Second Home Edition, Whitehouse Station, NJ, 2003) 10. Maya Tiwari, Women’s Power to Heal through Inner Medicine (Mother OM Media, 2007), Chapters 1-5. 11. Sher KS, Mayberry JF. Female fertility, obstetric and gynecological history in coeliac disease. A case control study. Digestion. 1994;55(4):Pages: 243-246. 12. Lansdorf, Nancy, M.D., A Women’s Best Medicine: Health, Happiness and Long Life Through Ayur-Veda, (Putnam Publishing, New York, NY, 1995): Pages: 41-43. 13. Sushruta Samhita-KL Bhishagratna Translator (Chaukhamba Orientalia, Varanasi, India, 1991), Pages 3-23 (I), 45-49 (II). 14. Lee, Dr. John, Natural Progesterone, The multiple Roles Of A Remarkable Hormone, (Jon Carpenter, 2001), Pages: 56-89. 15. C Augood, K Duckitt and AA TempletonSmoking and female infertility: a systematic review and meta-analysis Human Reproduction, Volume 13, Pages: 1532-1539. 16. Sher KS, Mayberry JF. Female fertility, obstetric and gynecological history in coeliac disease. A case control study. Digestion. 1994;55(4):Pages: 243-246. 17. Pasquali R, Patton L, Gambineri A, Obesity and infertility Curr Opin Endocrinol Diabetes Obse 2007 Dec;14(6):482-7. 18. Sushruta Samhita-KL Bhishagratna Translator (Chaukhamba Orientalia, Varanasi, India, 1991), Pages 3-23 (I), 45-49 (II). 19. Francine Grodstein, Marlene B. Goldmanet al Relation of Female Infertility to Consumption of Caffeinated Beverages American Journal of Epidemiology Volume 137, No. 12: Pages: 1353-1360. 20. Jorge E. Chavarro, M.D., Walter C. Willett, M.D., and Patrick J. Skerrett, The Fertility Diet, (McGraw Hill Professional, November 2007): Pages 33-36. 21. Jonathan L. Tilly and Richard N. Kolesnick, Sphingolipids, apoptosis, cancer treatments and the ovary: investigating a crime against female fertility Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids Volume 1585, Issues 2-3, (30th December 2002): Pages 135-138. 22. David Frawley, Yoga and Ayurveda, (Lotus Press, Twin Lakes, Wisconsin, 2000): Pages: 112-115. 23. Sher KS, Mayberry JF. Female fertility, obstetric and gynecological history in coeliac disease. A case control study. Digestion. 1994;55(4):Pages: 243-246. 24. A Cabau, DR Krulik. J Gynecol Obstet BiolReprod, (1990), 19,Pages: 96–101. 25. A Mundewadi, “Female Infertility, Ayurvedic Herbal Treatment”, (2009), 5, Pages: 141-145. 26. Chavarro JE, Rich-Edwards JW,et al, “Diet and lifestyle in the prevention of ovulatory disorder infertility” Obstet Gynecol. (November 2007);110(5):Pages 1050-1058. 27. Wurn BF, Wurn LJ, et al. 2004. Treating female infertility and improving IVF pregnancy rates with a manual physical therapy technique. MedGenMed. (June 18); 6(2):51. 28. Wurn BF, Wurn LJ, et al. 2008. Treating fallopian tube occlusion with a manual pelvic physical therapy. Altern Ther Health Med. (January-February);14(1):18-23. 29. Wurn BF, Wurn LJ, et al. 2004. Increasing orgasm and decreasing dyspareunia by a manual physical therapy technique. MedGenMed. (December 14);6(4):47. 30. AZ Steiner, M Terplan, , RJ Paulson,. Hum Reprod, (2005), 20, 1511. 31. Lee, Dr. John, Natural Progesterone, The multiple Roles Of A Remarkable Hormone, (Jon Carpenter, 2001), Pages: 56-89. 32. A Cabau, DR Krulik. J Gynecol Obstet BiolReprod, (1990), 19,Pages: 96–101.

The disease Gridhrasi is commonly seen in society as prominent problem ; in this condition patient becomes incapable to do his daily routine work because of severe pain from Kati pradesha (lumbar region) toPadanguli (foot).[1] As per data available 80% population in modern industrial society experience back pain at sometime during their life , fortunately in some of these its subsides within a month. But unfortunately as many as 70% of these pain reccurs , out of these many of them converts into Gridhrasi patients as time passes.The disease , Gridhrasi classified into two categories viz. Samanyaja (general)and Nanatmaja (specific) disease are those who are resulting to the vitiation of onedosha only. Charakacharya quoted Gridhrasi in Vataja ,NanatmajaVyadhi and also enumerated underMahagada(dreadful disorders with bad prognosis)that indicates difficulty to cure it. It is characterised by its distinct pain emerging from Sphikpradesha(gluteal region)and goes towards ParshaniPratyangulina(ankle joint and foot) of the affected side.[2]And Charak and Madhava mentioned the symptoms of Gridhrasi like Bhaktadvesha (aversion to food) , Gaurava(heaviness) , Tandra(drowsiness) , Aruchi(anorexia) , Mukhapraseka (salivation) in Vata – Kaphaja type Gridhrasi.[3] So indirectly Kaphaprakopanidana and Agnimandyahetu are to be considered.As per the modern medical science , Gridhrasi can be correlated with Sciatica due to its similarity in the symptoms of pain radiating along the course of sciatic nerve and is felt in the back , buttock, posterior aspect of thigh , leg and foot.[4] The commonest symtopms of the lumber disc prolapse are backache and Sciatica. When conservative treatment fails , surgery such as Microscopic lumbar discectomy or Fenestration or micordisectomy , Hemilaminectomy or full Laminectomy is done with due risk.[5] References 1. Charakatranslation ,ChoukhambaOrientelia , Varanasi. Chikitsasthana chapter 28 , pg.869 Samhita English 2. SushrutaSamhita English translation by P.V. Sharma ,Sutrasthana chapter 1st , pg. no.15. 3. Charakatranslation ,ChoukhambaOrientelia , Varanasi. Chikitsasthana chapter 28 , pg. 870 Samhita English 4. Outline of Orthopaedics , By John Crawford Adams & David L. Hamblen , 13th edition ; pg no.200,201,204. 5. Surgical Exposure in Orthopedics , illustration by Hugh .A. Thomas , 3rd edition , Jaypee Brother Medical Publication ; pg no.296,440,437. 6. Madhavnidanaed. By Vd.JadavjiTricumjiAcharaya ,ChoukhambaOrientelia , Varanasi.Chapter 22 , pg. no. 175 7. SushrutaSamhita English translation by P.V Sharma ,Sutrasthana chapter 12 , pg. no. 8. Textbook of Operative Neurosurgery , Ed. By Ravi Ramamurthi , K Sridhar , M.C Vasudevan , B.I Publication pvt ltd , New Delhi ; pg no. 1037 ,1040. 9. BhaishajyaRatnavali Vol.2 ed. By BrahmashankarMishra ,Choukhamba Sanskrit Bhawan , Varanasi. Chapter 26 , pg. no. 135 , 136. 10. ChakradattaHindiComm , ed. By Prof. RamanathDwivediChoukhamabaSanskritiseries , Varanasi. Chapter 22 ,pg 136. 11. HaritaSamhita by Vd.JaiminiPandey Hindi translation , 3rdsthana , chapter 22 , pg no. 380 , 381. 12. Yogratnakar Vol.1 by Dr.MadhamShetty Suresh Babu , English translation , Choukhamba Sanskrit series , Varanasi. Pg. no. 611. 13. DravyagunaVijnanaVol.2 ,Dr.J.L.Sastry , ChaukhambaOrentalia , Varanasi , pg.no. 108. 14. DravyagunaVijnanaVol.2 ,Dr.J.L.Sastry , ChaukhambaOrentalia , Varanasi ,pg. no. 399. 15. DravyagunaVijnanaVol.2 ,Dr.J.L.Sastry , ChaukhambaOrentalia , Varanasi ,pg. no.403. 16. DravyagunaVijnanaVol.2 ,Dr.J.L.Sastry , ChaukhambaOrentalia , Varanasi ,pg. no.418. 17. DravyagunaVijnanaVol.2 ,Dr.J.L.Sastry , ChaukhambaOrentalia , Varanasi ,pg. no.426. 18. Shekokar A. Jamnagar : Gujarat Ayurved University ; 2004. A Comparative study of Agnikarma and AjmodadiVati in management of Gridhrasi. 19. Yogithabali MR- Efficacy of Agnikarma (padmakanishtaanguli) and Kati basti in Gridhrasi - a comparative study(dissertation) RGUHS. Karnataka Bengaluru; 2006 20. Dr. RajankumarSahi – A comparative study of Agnikarma and Matrabasti in management of Gridhrasi( sciatica) ;2002.

Ayurveda has successful existence since time immemorial itself proves its scientific approach attributed to its unique Basic principle that remains unchanged till date. One of Such principle is ‘Doshpaka’. Acharya Madhava has elaborated concept as Doshpaka. Doshpaka has been given in relation to the Jwara Vyadhi where the Symptoms of vitiated Dosha decreases i.e. Dosha Prakruti Vaikrutyam, Laghvata in Jwara Lakshanas and Deha occurs, refreshing the Indriyas. Doshpaka had been given in context of Jwara Vyadhi but it is applied in other Vyadhis too. In this study, this basic principle in Bahupittakamla Vyadhi in 30 patients, considering Symptoms of the disease, Symptoms of the Doshpaka, along with pathological investigations in divided follow up from 0, 7, 14, 21, 28 day. As the disease runs in the body the symptoms of the disease regresses, returning of the Dosha to their Samyavastha, suggestive of Doshpaka the same changes were observed in the pathological values reduction of the values and Normalizing, or in some cases the Vyadhi may involve Dushayas to the deeper extent, symptoms becoming severe indicating Dhatupaka. Doshaprakruti Vaikrutyam was assessed in the patients by evaluating the Pitta Prakrit karma. References 1 Madhava Nidana of Madhavakara with the commentary Madhukosa by Vijayaraksita & Sriknthadatta Chaukhamba Surbharti Prakashan, Varanasi, 2014 2 Digestion And Metabolism In Ayurveda, Chowkhamba Krishnadas Academy, Varanasi, 2010 3 Dan L. Lango, Dennis L. Kasper, Anthony S. Fausi, Tephen L. Hauser, J. Larry Jamson, Joseph Loscalzo, Harrisons principle of Internal Medicine, 18th Edition 4 Harsh Mohan, Textbook of Pathology, Jaypee Brothers Medical Publishers (p) LTD, 5th Edition, 2005 5 Sushruta Samhita, Sushrutmarshini hindi vyakhya, Chaukhamba Surbharti Prakashan, Varanasi, 2010 6 Ashtang Hridaya, Nirmala- Hindi Vyakhya, Chaukhamba Surbharti Prakashan, Varanasi,2004

In Ayurveda Tundikeri is explained under diseases of oral cavity. This disease is grossly explained in Ayurvedic literature under classifications of Kantagata and Talugata roga. In contemporary science, it may be correlated to Tonsillitis. Tundikeri (tonsillitis) is commonly encountered now a days due to the dietary habits of taking spicy food, cold beverage, refrigerated milk products and cold climate. All people are equally prone basing on the immunity status. These factors coupled together results in recurrent episodes of disease. Tundikeri not only cripples children from majority of their enjoyable and learning movement but also makes adults to feel uneasy, restless and even bed ridden, if complication occurs. In Ayurveda Diseases can be diagnosed by the study of Nidana panchaka viz. Nidana (aetiology), Purvarupa (premonitory symptoms), Linga (actual symptoms), Upasaya (exploratory therapy) and Samprapti (pathogenesis). In the treatment point of view Samprapthi is very importent to selection of suitable drug. In this study it is explained Samprapti and Samprapti Vighatana of Tundikeri according to ayurvedic methodology References 1 Kaviraj Ambikadutta Shastri, Vaidya yadhavji Trikamji Acharya, Sushruta Samhitha, Chowkhamba Krishnadas academy,Varanasi 2008. Nidana sthana 16/42, Page No.387. 2. Prof. K.R.Srikantha Murthi, Ashtanga hridayam ,Chaukhambha Krishnadas Academy, Varanasi,2006 Utaratantra 21/47, Page No:193. 3. Kaviraj Ambikadutta Shastri, Vaidya yadhavji Trikamji Acharya, Sushruta Samhitha, Chowkhamba Krishnadas academy,Varanasi 2008. Nidana sthana 16/44, Page No.387. 4. Bernstein JM, Gorfien J and Brandtzaeg P. The immunobiology of the tonsils and adenoids. Ogra Mucosal immunology. Academic Press, San Diego. 1999:1339-1362. 5. Mckerrow WS. Disease of tonsil. In: Gleeson M, Browning GG, Burton MJ, Clarke R (eds): Scott Brown’ Otolaryngology, Head and Neck Surgery1 (B): Seventh edition. London: Hodder Education; 2008:1219-1220. 6. Sebastia LIA, Ramirez MJF, Molla CL, Llatas C,Mocholi P, Ruiz MD, Ferriol JE and Martinez RL.Changes in immunoglobulin levels following adenoidectomy and tonsillectomy. Acta Otolaryngol 2004 ;55: 404-408. 7. Brook I, Youson P. Quantitative measurement of B-lactamase in tonsils of children with recurrent tonsillitis. Acta Otolaryngol (Stockh) 1984:536-59. 8 Kashinath Shastri, Dr. Gorakhnath chaturvedi, Charaka samhita of Agnnivesa,revised by Charaka and Drdhabala , Chowkhamba Bharti Academy, Varanasi 2001. Vimana sthana, 5/24.Page No: 596. 9. Kaviraj Ambikadutta Shastri, Vaidya yadhavji Trikamji Acharya, Sushruta Samhitha, Chowkhamba Krishnadas academy, Varanasi 2008. Nidana sthana 11/3. Page No: 350. 10.Kashinath Shastri, Dr. Gorakhnath chaturvedi, Charaka samhita of Agnnivesa,revised by Charaka and Drdhabala , Chowkhamba Bharti Academy, Varanasi 2001. Chikitsa sthana, 12/87.Page No: 311. 11.Dr. M. Rama Sunder rao, text book of Shalya Tantra Vignamam,2002,page No.397. 12. Prof. K.R.Srikantha Murthi, Ashtanga hridayam ,Chaukhambha Krishnadas Academy, Varanasi,2006 Utaratantra 21/1, Page No:184. 13. Prof. K.R.Srikantha Murthi, Ashtanga hridayam ,Chaukhambha Krishnadas Academy, Varanasi,2006 Utaratantra 21/2 Page No:184.

Shift work allows for continuous services and production, 24 hours per day. Examples of such round-the-clock work include health care, customs and immigration, telecommunication, electrical utilities, and transportation etc.People vary in how they cope with shift work depending on their health, fitness, age, lifestyle, and domestic responsibilities; some adapt well, others do not. It is possible to alter our behavior or make lifestyle changes that may make shift work more tolerable 1. References 1. 1. Dr. GhadekarGB,Sushrutsamhitasarirsthanam, garbhvyakarannaamadhaya 4/34., reprint 2012,Meharchandlaxman das publication, New delhi. 2.Dr.BrahmanandTripathi, Charaksamhita, sutra sthana, asthonindatiyapurushadhaya 21/35. Vol-1 edition 2012 Chaukhambasurbharti publication, Varanasi. 3.Dr.BrahmanandTripathi, Chakradutta,Charaksamhita, sutra sthana, asthonindatiyapurushadhaya 21/59. Vol-1 edition 2012 Chaukhambasurbharti publication, Varanasi. 4Dr.BrahmanandTripathi, Charaksamhita, sutra sthana, navegaandhardiyanadhaya 7/10.Vol-1 edition 2012 Chaukhambasurbharti publication, Varanasi. 5.Dr.BrahmanandTripathi, Charaksamhita, sutra sthana, asthonindatiyapurushadhaya 21/37. Vol-1 edition 2012 Chaukhambasurbharti publication, Varanasi. 6.kaviraajaatridevagupt, Asthanghridayam, sutrasthana, annarakshadhya 7/49-51. reprintChaukhamba Sanskrit sansthan, Varanasi. 7.Dr.BrahmanandTripathi, Charaksamhita, sutra sthana, asthonindatiyapurushadhaya 21/50. Vol-1 edition 2012 Chaukhambasurbharti publication, Varanasi. 8.Kaviraajaatridevagupt, Asthanghridayam, sutrasthana, annarakshadhya 7/65. reprintChaukhamba Sanskrit sansthan, Varanasi. 9. Dr. Ghadekar GB, Sushrutsamhitasarirsthanam, garbhvyakarannaamadhaya 4/41. reprint2012,Meharchand laxman das publication, New delhi. 10.Kaviraajaatridevagupt, Asthanghridayam, sutrasthana, annarakshadhya 7/65 reprintChaukhamba Sanskrit sansthan, Varanasi. 11. Dr.BrahmanandTripathi, Charaksamhita, sutra sthana, asthonindatiyapurushadhaya 21/41-42Vol-1 edition 2012 Chaukhambasurbharti publication, Varanasi. 12.Dr.BrahmanandTripathi, Charaksamhita, sutra sthana, asthonindatiyapurushadhaya 21/52-53. Vol-1 edition 2012 Chaukhambasurbharti publication, Varanasi.

Inflammation of epididymis & testis is called as epididymo-orchitis.bacterial infection from kidney,bladder, urethra(UTI),prostate,STD (syphilis, gonorrhoea) are frequent causes.Mumps,another common cause in children for orchitis.clamediasis, E.coli are the commonest causative organisms.Tuburculosis is another common cause for epididymo-orchitis. symptoms includes pain, swelling, & redness in affected side of scrotum.may or may not be associated with fever or fever with chills.affected side becomes red hot, firm & tender`(1). Treatment includes broad spectrum antibiotics,analgesics & anti-inflammatory drugs rest, scrotal support is also needed.if tubercular infection is present AKT is to be started.with this standerd treatment patients usually gets relief from pain, fever but firmness swelling may take several months to resolve completely. Few Patients however does not respond to this standard treatment.condition may lead to abscess formation, iscaemic damage to testis & atrophy of testis`(2). in such condition surgical intervention like I&D ,orchidectomy is needed as per condition.So effective management of acute & chronic epididymo-orchitis is still a problem for surgeon inspite of higher antibiotics. Ayurveda has excilent solution in such type of resistant cases not responding to standred conservative management.If this standred treatment is added on by leech application,symptoms like pain,tenderness,swelling,firmness are reduced to significant level.In present case study we got fabulous result after leech application. 1. References 1. 1. “epididymitis & orchitis an overview”American family physician,79 pp 583-587,2009,view at Google scholor.view at scopus. 2. “Testicular infarction secondary to epididymo-orchitis ,sureyya Burcu.Gorkem,imaging science today”.2009 nwww.imagingsciencetoday.com. 3. Maharshi Sushruta’s sushrut samhita part 1;edited with ayurved tatwa sandipika sharirsthana adhyaya 8 shloka 23; edited by Ambikadatta Shastri; 14th edition reprint 2003 chaukhamba sanskrit sansthan, Varanasi page no.67 4. Sharandhar samhita madhyam khand adhyaya 7 shloka 82-83 Gudarthadipika commentary by Parshuramshstri vidyasagar.

T. cordifolia (Gulancha) is an available and well known herb all over the world. It is traditionally use for various aliment like fever, vomiting, diabetes, jaundice, anaemia, polyuria and skin diseases etc. It is indicated as Medhyarasayana (brain tonic), digestive, appetite stimulant and carminative for digestive system. It has potent rejuvenative, neuroprotective, hypoglycemic, immuno modulatory , anti inflammatory effect. Though various indications are found in classical text, experimental and controlled trials are needed to determine its real efficacy. The Guduchi plant, its properties, mechanism of action and clinical uses are briefly reviewed in this article 1. References 1. Mittal Jitendra, Sharma Madan Mohan, Batra Amla, Tinospora cordifolia: a multipurpose medicinal plant- A review; Journal of Medicinal Plants Studies 2014; 2(2):80-86. 2. Sharma, P.V, Dravyaguna Vijnan, Reprint 1999, Choukhamba Bharati Academy,Varanasi, p -761. 3. Kirtikar KR, Basu BD; Indian Medicinal Plants.2nd Edition , Vol.-1, 2012,Periodical Book Agency, Delhi ; p-77 4. Nadkarni KM, Nadkarni AK; Indian Materia Medica. 3rd Edition , Vol.- 1,1976, M/S Popular Prakasan Pvt. Ltd, Delhi, p- 1220 5. The Ayurvedic Pharmacopoeia of India; Part1, Vol.1,Ministry of Health &Family Welfare, Govt. of India; New Delhi; First ed.1990, Reprint 2001; p -41 6. Sharma, P.V, Dravyaguna Vijnan; Reprint 1999; Choukhamba Bharati Academy, Varanasi. P- 761 7. Singh S.S, Pandey S.C., Srivastava S., Gupta.S., Patro B. Ghosh A.C.;TINOSPORA CORDIFOLIA: CHEMISTRY AND MEDICINAL PROPERTIES(GUDUCHI) ;Indian Journal of Pharmacology 2003; 35: 83-91 8. Sabnis Mukund, Chemistry and Pharmacology of Ayurvedic Medicinal Plant;2nd Edition ,Vol 12;Chaukhamba Amarabharati Prakashan,Varanasi, 2006.p-83. 9. Wadkar KA, Magdum CS, Patil SS, Naikwade NS. Anti diabetic potential and Indian medicinal plants. J Herbal Med Toxicol 2008; 2:45-50. 10. Rohit Sharma, Hetal Amin, Galib, Pradeep Kumar Prajapati; Antidiabetic claims of Tinospora cordifolia (Willd.) Miers: critical appraisal and role in therapy; Asian Pacific Journal of Tropical Biomedicine; 2015; 5(1): 68-78 11. Database on Medicinal Plants Used in Ayurveda, Vol.3, CCRAS, New Delhi, Reprint 2005; p -256. 12. Sharma.P.V, Dhanwantary Nighantu (Hindi), 1st edition 1982, Chowkhamba oriental; Varanasi;p-34 13. Narahari P,Raj Nighantu, Edited by Indradev Tripathi , 1st Edition, Krishna Das Academy, Varanasi, p.- 29, 416, 443. 14. Pandey.G.S, Bhabprakash Nighantu, 4thEdition1969, Chowkhamba Snaskrit Snasthan, Varanasi,p -206,270,612. 15. 15.Vaishya S.B;Shaligram Nighantu;Khemraj Srikrishnadas Venkteswar Steam Press;Bombay 1981;p- 23,187,575. 16. Vaidya Bapala Gl,Nighantu Adarsha, 1st Edition 1968, Chowkhamba Vidyabhavan, Varanasi, Uttarardha, p -35&258. 17. Nripa Madanpal, Madanpal Nighantu (Hindi);Ed 1954 Ganga Vishnu Srikrishna Das Press, Bombay; pp.- 115 &993. 18. Sharma P.V, Kaidev Nighantu, 1st Edition 1979, Chowkhamba Orienta, Varanasi, Delhi; p.- 5, 260, 284 19. Pandit.Datta.S, Sankar Nighantu, 1st Edition 1935, Banousadhi Bhandar, Jabbalpur,p-72. 20. Sharma, P.V;Priya Nighantu; 1st edition 1983;Chowkhamba Surabharati Prakasan; Varanasi,p-60.

Triphalaadi yoga is a combination of eleven dried herbs i.e. Haritaki, Bibhitaki, Amalaki, Yastimadhu, Gokshura, Guduchi, Haridra, Daruharidra, Shunthi, Tulsi and Punarnava in powder form which is administered as a rasayana therapy in patients of CVS. These eleven drugs chosen for this study is an Anubhoota yoga from the Shalakya Tantra Department of I.P.G.T& R.A, Jamnagar and has the solid backing of previous researches for their most important individual activities. The body is made up of Panchamahabhuta so the plants from which Ayurvedic drugs are extracted. In the present study author try to evaluate how the composition of Panchamahabhuta changes before and after the Bhavna of the drug with the help of the pharmacognostical parameters like acicular crystals of Punarnava which are rarely found after the Bhavna of the drug and and also evaluate the differences in the pharmaceutical profile before and after Bhavna like loss on drying, ash value, acid insoluble ash, water soluble extract, methanol soluble extract, pH and HPTLC. 1. References 1. 1. www.sankarnetralaya.org/patient care-cvc.html 2. Sivbalaji et al: Ayurvedic Approach on Computer Vision Syndrome IAMJ: Volume 1; Issue 3; May – June 2013 3. Madhulika Priya, Critical review on importance of bhavana in rasoushadh , IAMJ., July - August-2014; 2(4). 4. Rege NN, Thatte UM, Dahanukar SA. Adaptogenic properties of six Rasayana herbs used in Ayurvedic medicine. Phytother Res., 1999; 13(4): 275-91. 5. http://dx.doi.org/10.1002/(SICI)1099-1573(199906)13:4<275::AID-PTR510>3.3.CO;2-J. 6. Suresh Kumar Gupta, V. Kalaiselvan, Sushma Srivastava, Shyam S. Agrawal, Rohit Saxena. Evaluation of anticataract potential of Triphala in selenite induced cataract: In vitro and in vivo studies. J Ayurveda Integr Med., 2010; 1(4): 280-286. http://dx.doi.org/10.4103/0975-9476.74425. 7. Megha Saraswat, Palla Suryanarayana and Geereddy Bhanuprakash Reddy. Antiglycating potential of Zingiber officinalis and delay of diabetic cataract in rats. Mol Vis., 2010; 16: 1525-1537. 8. Devasagayam TP, Tilak JC, Boloor KK, Sane KS, Ghaskadbi SS, Lele RD. Free radicals and antioxidants in Human Health: Current status and future prospects. J Assoc Physicians India., 2004; 52: 794-803. 9. Agrawal B, Das S, Pandey A. Boerhaavia diffusa Linn.: A review on its phytochemical and pharmacological profile. Asian J Appl Sci., 2011; 4: 663-84. http://dx.doi.org/10.3923/ajaps.2011.663.684. 10. Saurabh Chhatre, Tanuja Nesari, Gauresh Somani, Divya Kanchan, Sadhana Sathaye. Phytopharmacological overview of Tribulus terrestris. Pharmacogn Rev., 2014; 8(15): 45-51. http://dx.doi.org/10.4103/0973-7847.125530. 11. .Seher Cimen Ozgen, Dikmen Dokmeci, Meryem Akpolat, Cetin Hakan Karadag1, Ozgur Gunduz, Hakan Erbaş et al. The Protective Effect of Curcumin on Ionizing Radiation induced Cataractogenesis in Rats. Balkan Med J., 2012; 29: 358-63. Bharat B. Aggarwal, Sahdeo Prasad, Simone Reuter. 12. Identification of Novel Antiinflammatory Agents from Ayurvedic Medicine for Prevention of Chronic Diseases: "Reverse Pharmacology" and "Bedside to Bench" Approach. Curr Drug Targets., 2011; 12(11): 1595-1653. http://dx.doi.org/10.2174/138945011798109464. 13. Wallis TE. Text book of Pharmacognosy. 5th ed. New Delhi: CBS Publishers & Distributors., 2002; 123- 32: 210-5. 14. Trease GE, Evans WC. Pharmacognosy. 12th ed. Eastbourne, U.K: Bailliere Tindall., 1983; 95-99: 512-47. 15. Anonymous. The Ayurvedic Pharmacopoeia of India. part 2, vol 2, Appendices 1st ed. New Delhi: Govt. of India Publication., 2008; 233-5. 16. Gopinathan G et al. / Detailed Comparative Pharmacognostical Evaluation of Different Combinations Formulation of Triphala